Diagnosis of tuberculosis.

dc.contributor.authorLodha, Ren_US
dc.contributor.authorKabra, S Ken_US
dc.contributor.authorSeth, Ven_US
dc.date.accessioned2000-02-29en_US
dc.date.accessioned2009-05-30T13:57:18Z
dc.date.available2000-02-29en_US
dc.date.available2009-05-30T13:57:18Z
dc.date.issued2000-02-29en_US
dc.description44 references.en_US
dc.description.abstractDiagnosis of tuberculosis in children is usually based on clinical signs and symptoms, chest roentgenogram, tuberculin testing and history of contact with adult patients. The diagnostic tests for tuberculosis can be broadly divided into 2 groups: demonstration/isolation of Mycobacterium tuberculosis or one of its components [Ziehl Neelson (ZN) staining, special stains, cultures, polymerase chain reaction]; demonstration of host's response to exposure to M. tuberculosis (Mantoux test, serodiagnosis). The yield of tests used for demonstration of mycobacterium or its components is poor because of pauci-bacillary nature of disease in children. Diagnostic use of PCR is still experimental. Serodiagnosis does not have acceptable sensitivity and specificity hence, at present, does not have any role in diagnosis of tuberculosis in children. The diagnosis is suspected on history and a combination of imaging studies and Mantoux test still remains the most widely used investigation.en_US
dc.description.affiliationDepartment of Pediatrics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi.en_US
dc.identifier.citationLodha R, Kabra SK, Seth V. Diagnosis of tuberculosis. Indian Journal of Pediatrics. 2000 Feb; 67(2 Suppl): S3-8en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/82192
dc.language.isoengen_US
dc.source.urihttps://medind.nic.in/icb/icbai.shtmlen_US
dc.subject.meshChilden_US
dc.subject.meshChromatographyen_US
dc.subject.meshHumansen_US
dc.subject.meshMycobacterium tuberculosis --isolation & purificationen_US
dc.subject.meshPolymerase Chain Reactionen_US
dc.subject.meshSerologic Testsen_US
dc.subject.meshTuberculin Testen_US
dc.subject.meshTuberculosis, Pulmonary --diagnosisen_US
dc.titleDiagnosis of tuberculosis.en_US
dc.typeJournal Articleen_US
dc.typeReviewen_US
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