A Comparative Evaluation Of Dexamethasone As An Adjunct To Bupivacaine And Levobupivacaine For Supraclavicular Brachial Plexus Block Using Peripheral Nerve Stimulator

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dc.contributor.authorAbu, Nadeemen_US
dc.contributor.authorVarshney, Varun Ken_US
dc.contributor.authorHaleem, Shahlaen_US
dc.contributor.authorSingh, Abhisheken_US
dc.date.accessioned2019-12-02T10:30:42Z
dc.date.available2019-12-02T10:30:42Z
dc.date.issued2018-01
dc.description.abstractBackground:Dexamethasone appears to be effective in prolonging the duration of analgesia from supraclavicular brachial block using levobupivacaine or Bupivacaine. Long acting local anaesthetic, Bupivacaine is associated with cardiac and central nervous system toxicity which prompted the researchers to develop new local anaesthetic agent with a profile similar to bupivacaine but avoiding the toxic effects. Therefore, the aim of the present study is to test the hypothesis that adding dexamethasone significantly prolongs the duration of analgesia for levobupivacaine and bupivacaine and the magnitude of the effect differs among the two local anaesthetics. Methods: A prospective, randomized study was undertaken at JN Medical College. 120 patients posted for upper limb surgeries under Supraclavicular Brachial Plexus Block were assigned into four groups, each containing 30 patients. Group I received 25 ml Bupivacaine 0.5% and 2ml NS. Group II received 25 ml of Bupivacaine 0.5% and 2ml dexamethasone(8mg) .Group III received 25 ml of Levobupivacaine 0.5% and 2ml NS. Group IV received 25 ml of Levobupivacaine 0.5% and2ml dexamethasone (8mg). Results:Dexamethasone significantly prolonged the duration of analgesia of both levobupivacaine and bupivacaine. Conclusion:Dexamethasone prolongs analgesia in supraclavicular blocks using either levobupivacaine or bupivacaine. Considering the less cardiotoxic profile of levo-bupivacaine it should be preferred over bupivacaine.en_US
dc.identifier.affiliationsAssistant Professor, Department of Anaesthesiology, Faculty of Medicine, J. N. Medical College, A.M.U., Aligarh 202002, U.P., Indiaen_US
dc.identifier.affiliationsSenior Resident, Department of Anaesthesiology, Faculty of Medicine, J. N. Medical College, A.M.U., Aligarh 202002, U.P., Indiaen_US
dc.identifier.affiliationsProfessor, Department of Anaesthesiology, Faculty of Medicine, J. N. Medical College, A.M.U., Aligarh 202002, U.P., Indiaen_US
dc.identifier.affiliationsMD Student, Department of Anaesthesiology, Faculty of Medicine, J. N. Medical College, A.M.U., Aligarh 202002, U.P., India.en_US
dc.identifier.citationAbu Nadeem, Varshney Varun K, Haleem Shahla, Singh Abhishek. A Comparative Evaluation Of Dexamethasone As An Adjunct To Bupivacaine And Levobupivacaine For Supraclavicular Brachial Plexus Block Using Peripheral Nerve Stimulator. Annals of International medical and Dental Research. 2018 Jan; 4(1): 1-6en_US
dc.identifier.issn2395-2822
dc.identifier.issn2395-2814
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/187643
dc.languageenen_US
dc.publisherSociety for Health Care & Research Developmenten_US
dc.relation.issuenumber1en_US
dc.relation.volume4en_US
dc.source.urihttps://www.doi.org/10.21276/aimdr.2018.4.1.AN1en_US
dc.subjectBupivacaineen_US
dc.subjectDexamethasoneen_US
dc.subjectLevobupivacaineen_US
dc.titleA Comparative Evaluation Of Dexamethasone As An Adjunct To Bupivacaine And Levobupivacaine For Supraclavicular Brachial Plexus Block Using Peripheral Nerve Stimulatoren_US
dc.typeJournal Articleen_US
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