Small cell lung cancer: an update on therapeutic aspects.

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dc.contributor.authorBhutani, Manishaen_US
dc.contributor.authorPathak, Ashutosh Kumaren_US
dc.contributor.authorMohan, Ananten_US
dc.contributor.authorGuleria, Randeepen_US
dc.contributor.authorKochupillai, Vinoden_US
dc.date.accessioned2006-01-18en_US
dc.date.accessioned2009-05-27T10:28:14Z
dc.date.available2006-01-18en_US
dc.date.available2009-05-27T10:28:14Z
dc.date.issued2006-01-18en_US
dc.description67 references.en_US
dc.description.abstractSmall cell lung cancer comprises approximately 20% of all lung cancers and continues to be a difficult management issue. More than two-thirds of cases present with extensive disease, which has spread beyond the himithorax and regional ipsilateral nodes. While response rates to chemotherapy are relatively high, durable responses are rare, and long-term survival rates are anecdotal. Although many attempts have been made to develop new therapies, a combination of etoposide with either cisplatin or carboplatin remains the most widely used first-line therapy for extensive disease. For those with limited disease, chemotherapy with concomitant radiotherapy (given with the first or second cycles of chemotherapy) is considered the standard of care. Over the last decade, several new drugs and targeted agents have been identified with the aim to improve outcome of this malignancy. In this review we highlight recent developments in the management of this tumour.en_US
dc.description.affiliationDepartment of Medical Oncology, Institute Rotary Cancer Hospital, New Delhi, India.en_US
dc.identifier.citationBhutani M, Pathak AK, Mohan A, Guleria R, Kochupillai V. Small cell lung cancer: an update on therapeutic aspects. The Indian Journal of Chest Diseases & Allied Sciences. 2006 Jan-Mar; 48(1): 49-57en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/30125
dc.language.isoengen_US
dc.source.urihttps://medind.nic.in/iae/iaem.shtmlen_US
dc.subject.meshCamptothecin --analogs & derivativesen_US
dc.subject.meshCarboplatin --therapeutic useen_US
dc.subject.meshCarcinoma, Small Cell --drug therapyen_US
dc.subject.meshCisplatin --therapeutic useen_US
dc.subject.meshEtoposide --therapeutic useen_US
dc.subject.meshHumansen_US
dc.subject.meshLung Neoplasms --drug therapyen_US
dc.subject.meshNeoplasm Stagingen_US
dc.subject.meshRadiotherapyen_US
dc.titleSmall cell lung cancer: an update on therapeutic aspects.en_US
dc.typeJournal Articleen_US
dc.typeReviewen_US
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