Hypothalamic hamartoma presenting as central precocious puberty: a rare case report

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dc.contributor.authorSharma, Priyankaen_US
dc.contributor.authorAcharya, Nishanten_US
dc.contributor.authorGuleria, Trilok C.en_US
dc.date.accessioned2020-09-24T07:48:38Z
dc.date.available2020-09-24T07:48:38Z
dc.date.issued2020-07
dc.description.abstractPrecocious puberty is defined as children attaining puberty more than 2.5 to 3 standard deviations (SD) earlier than the median age, or before the age of eight years in girls and nine years in boys. Hypothalamic hamartoma (HH) are rare, non progressive tumor like malformation. Precocious puberty due to HH occurs particularly at early ages, even 2 or 3 years. Treatment options for isolated CPP due to HH include GnRH analogs agonists continuously stimulates pituitary gonadotrophs, which further help in decreasing and desensitizing the release of LH, and to a lesser extent, FSH till the time puberty naturally set in. We present a case of precocious puberty due to hypothalamic hamartoma in 3 years old girl. Treated with GnRH analog lupirode and responded well to treatment with cessation of menstruation and reduction in breast size.en_US
dc.identifier.affiliationsDepartment of Obstetrics and Gynecology, Bhandari Hospital Hamirpur, Himachal Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Pediatrics, Dr Radhakrishnan Government Medical College Hamirpur, Himachal Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Otorhinolaryngology, Dr Radhakrishnan Government Medical College Hamirpur, Himachal Pradesh, Indiaen_US
dc.identifier.citationSharma Priyanka, Acharya Nishant, Guleria Trilok C.. Hypothalamic hamartoma presenting as central precocious puberty: a rare case report. International Journal of Contemporary Pediatrics. 2020 Jul; 7(7): 1634-1637en_US
dc.identifier.issn2349-3283
dc.identifier.issn2349-3291
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/204695
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber7en_US
dc.relation.volume7en_US
dc.source.urihttps://dx.doi.org/10.18203/2349-3291.ijcp20202631en_US
dc.subjectGonadotrophsen_US
dc.subjectHypothalamic hamartomaen_US
dc.subjectLupirodeen_US
dc.subjectPrecociousen_US
dc.titleHypothalamic hamartoma presenting as central precocious puberty: a rare case reporten_US
dc.typeJournal Articleen_US
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