The outcome of primary percutaneous coronary intervention in patients with stent thrombosis

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dc.contributor.authorKumar, Mukeshen_US
dc.contributor.authorShar, Ghulam Shabbiren_US
dc.contributor.authorKumar, Rajesh Shaikhen_US
dc.contributor.authorAbdul, Hakeemen_US
dc.contributor.authorIshaque, Haroonen_US
dc.contributor.authorKhan, Naveedullahen_US
dc.contributor.authorFarooq, Fawaden_US
dc.contributor.authorSaghir, Tahiren_US
dc.contributor.authorAshraf, Tariqen_US
dc.contributor.authorKarim, Musaen_US
dc.date.accessioned2023-07-21T11:36:56Z
dc.date.available2023-07-21T11:36:56Z
dc.date.issued2022-12
dc.description.abstractBackground: Primary percutaneous coronary intervention (PCI) is a recommended management strategy for patients with de novo ST-segment elevation myocardial infarction (STEMI). Still, the efficacy of primary PCI in-stent thrombosis (ST) induced STEMI is unclear. The aim was to assess the clinical characteristics and the in-hospital outcomes of patients undergoing primary PCI for STEMI caused by acute, sub-acute, or late ST. Methods: A sample of hundred consecutive patients who presented with STEMI due to ST were included in this study. The angiographic evidence of a flow-limiting thrombus or total vessel occlusion (thrombolysis in myocardial infarction (TIMI) flow grade 0 to II) at the site of the previous stent implant was taken as ST. Primary PCI was performed, and all enrolled patients and in-hospital mortality were observed. Results: Male patients were 69, and the mean age was 58.9 ± 7.78 years. ST was categorized as acute in 40 patients, sub-acute in 53, and late in the remaining seven patients. Killip class III/IV was observed in 45 patients. Dissection was observed in 25, under deployment in 74, and/or malposition in 24 patients. Thrombus aspiration was performed in 97, plain old balloon angioplasty in 76, and stenting in 22 patients. Final TIMI III flow was achieved in 32 patients. During a mean hospital stay of 4.93 ± 2.46 days, the mortality rate was 27%. Conclusion: In-hospital mortality after primary PCI was observed in more than 1/4th of the patients with STEMI due to ST undergoing primary PCIen_US
dc.identifier.affiliationsNational Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistanen_US
dc.identifier.citationKumar Mukesh, Shar Ghulam Shabbir, Kumar Rajesh Shaikh, Abdul Hakeem, Ishaque Haroon, Khan Naveedullah, Farooq Fawad, Saghir Tahir, Ashraf Tariq, Karim Musa. The outcome of primary percutaneous coronary intervention in patients with stent thrombosis. Indian Heart Journal. 2022 Dec; 74(6): 464-468en_US
dc.identifier.issn0019-4832
dc.identifier.issn2213-3763
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/220945
dc.languageenen_US
dc.publisherCardiological Society of Indiaen_US
dc.relation.issuenumber6en_US
dc.relation.volume74en_US
dc.source.urihttps://doi.org/10.1016/j.ihj.2022.11.003en_US
dc.subjectST-Segment elevation myocardial infarctionen_US
dc.subjectStent thrombosisen_US
dc.subjectPrimary percutaneous coronaryen_US
dc.subjectinterventionen_US
dc.subjectMortalityen_US
dc.titleThe outcome of primary percutaneous coronary intervention in patients with stent thrombosisen_US
dc.typeJournal Articleen_US
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