Bacteriological Aspect of Bile in Cholecystectomy Patients
dc.contributor.author | Sunkaria, Babu Lal | en_US |
dc.contributor.author | Jamwal, Punit | en_US |
dc.contributor.author | Malhotra, Sita | en_US |
dc.contributor.author | Sharma, Sanjeev | en_US |
dc.contributor.author | Anant, Sarabjot Singh | en_US |
dc.contributor.author | Thomas, Chithra | en_US |
dc.contributor.author | Neki, N. S. | en_US |
dc.date.accessioned | 2020-01-02T06:07:40Z | |
dc.date.available | 2020-01-02T06:07:40Z | |
dc.date.issued | 2019-03 | |
dc.description.abstract | Cholecystectomy is currently a frequent performed operation. The presence of gallstones within either the gallbladder or biliary tree is associated with the bacterial colonization of the bile. Acute cholangitis spans a continuous clinical spectrum and can progress from a local biliary infection to advanced disease with sepsis and multiple organ dysfunction syndrome. Therefore, it is important to know the microbiological flora of the gallbladder before prophylactic antibiotics are given. Aim and objectives: 1.To evaluate the bacteriological profile of bile in patients undergoing cholecystectomy. 2. To determine the appropriate antibiotics for prophylaxis in cholecystectomy patients based on the bacteriological profile of bile in our study. Methods: The study was a prospective study carried out in Guru Nanak Dev Hospital, Amritsar. A total of 100 patients undergone cholecystectomy who met the inclusion criteria were included in the study. Bile was aspirated from all patients, this collected bile from gallbladder was transported to the Microbiology Department in 5cc sterile syringe. The specimen was evaluated to find out whether it is sterile or has any bacteria present. Sensitivity of isolated organisms was done against antibiotics. Results: 25 patients showed positive bile culture (25%), whereas bile was sterile in 75 patients (75%). E.Coli was the most common isolated bacteria (60%) followed by Enterococcus (20%), Staph Aureus (8%), Salmonella (8%) and Pseudomonas (4%). Postoperative wound infection was more common (20%) in group of patients with isolated organisms from bile. Conclusion: 25% of bile samples were culture positive. E coli was the most common aerobic bacteria to be isolated from the bile culture . E. coli, salmonella and pseudomonas were most sensitive to piperacillin + tazobactum and imipenum (100%). E. coli also showed sensitivity to amikacin and gentamicin (73.33% each). Enterococcus was most sensitive to linezolid and ampicillin + salbactum (100%) followed by gentamicin and amoxicillin + clavulanate (80% each). Staphylococcus was most sensitive to linezolid (100%). Antimicrobial susceptibility of potential causative organisms and the local susceptibility pattern must be taken into consideration when prescribing drugs to patients with biliary disease. | en_US |
dc.identifier.affiliations | Associate Professor, Department of Surgery, GMC, Amritsar. | en_US |
dc.identifier.affiliations | Junior Resident, Department of Surgery, GMC, Amritsar. | en_US |
dc.identifier.affiliations | Associate professor, Department of Microbiology, GMC, Amritsar. | en_US |
dc.identifier.affiliations | Professor and Head, Department of Surgery, GMC, Amritsar. | en_US |
dc.identifier.affiliations | Professor of Medicine, Govt. Medical College, Amritsar. | en_US |
dc.identifier.citation | Sunkaria Babu Lal, Jamwal Punit, Malhotra Sita, Sharma Sanjeev, Anant Sarabjot Singh, Thomas Chithra, Neki N. S.. Bacteriological Aspect of Bile in Cholecystectomy Patients. Annals of International medical and Dental Research. 2019 Mar; 5(2): 16-20 | en_US |
dc.identifier.issn | 2395-2822 | |
dc.identifier.issn | 2395-2814 | |
dc.identifier.place | India | en_US |
dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/188812 | |
dc.language | en | en_US |
dc.publisher | Society for Health Care & Research Development | en_US |
dc.relation.issuenumber | 2 | en_US |
dc.relation.volume | 5 | en_US |
dc.source.uri | https://doi.org/10.21276/aimdr.2019.5.2.SG6 | en_US |
dc.subject | Cholelithiasis | en_US |
dc.subject | Cholecystectomy | en_US |
dc.subject | Bile culture and Sensitivity | en_US |
dc.title | Bacteriological Aspect of Bile in Cholecystectomy Patients | en_US |
dc.type | Journal Article | en_US |
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