Deciphering the Upshots of Single and Second Dose of ChAdOx1-S Vaccination among Patients Hospitalized with COVID-19: A Multidimensional Approach

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Date
2023-09
Journal Title
Journal ISSN
Volume Title
Publisher
International Journal of Contemporary Medical Research
Abstract
Severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) is a dangerous infection throughout the world, despite the availability of affordable and effective management, remaining one of the major causes of death from a single infectious agent worldwide. To mitigate the backlash of the virus on public health the effect of single and second dose of ChAdOx1-S (Verity Pharmaceuticals Inc/Serum Institute of India, in partnership with AstraZeneca Canada Inc) vaccination or covishieldhas been advocated. It has been elucidated via different biochemical (LFT, KFT, and glucose)hematological (CBC) and antibody analysis (antibodies to SARS-CoV-2 IgG) to gain the outcome of single and second dose. Our study also provides empirical estimates of the effect of vaccination on the different age groups by estimation of values of these tests. The present study shows that simple, inexpensive, highly significant and specific tests should be employed routinely to check the etiology in patients of covid-19. This finding could be helpful in early clinical decision-making for the management of these patients
Description
Keywords
Antibodies, Biochemical, Coronavirus 2 (SARSCoV-2), Hematological, Vaccination
Citation
Shah Mohd Younus, Bhat Waseem Feeroze, Singh Harminder, Singh Gurjinder, Bhat Mohd Yunis Saleem, Borole Kumudini, Azad Tariq PArvaiz . Deciphering the Upshots of Single and Second Dose of ChAdOx1-S Vaccination among Patients Hospitalized with COVID-19: A Multidimensional Approach. International Journal of Contemporary Medical Research. 2023 Sep; 10(9): 11-19