A Prospective, Cross-sectional, Multicenter, Observational, Questionnaire-based Survey to assess the Knowledge, Awareness, Attitude and Practice of Physicians while Prescribing Proton Pump Inhibitor (PPI) Drugs for Acid Peptic Disease

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dc.contributor.authorPebbili, Kranthi Kiranen_US
dc.contributor.authorPendurthi, Bharadwajaen_US
dc.contributor.authorBhagat, Seemaen_US
dc.date.accessioned2023-06-17T08:34:32Z
dc.date.available2023-06-17T08:34:32Z
dc.date.issued2022-07
dc.description.abstractGoal : This is a subjective survey to assess the knowledge, awareness, and practices (KAP) of physicians while prescribing Proton pump inhibitors (PPI) in acid peptic disorder (APD) patients in India. Background : APD represents a variety of gastric anomalies in which PPIs form the mainstay of management. Many of the APD patients are associated with comorbidities, resulting in polypharmacy and increased risk of drugdrug interactions. Therefore, it is essential that physicians be aware of PPI drug interactions while prescribing them to patients with comorbidities. In developing countries like India, studies assessing the KAP of Physicians are limited. Study Design : This questionnaire-based study consisted of 3 domains: (A) Study objectives and consent; (B) Participants’ socio-demographic details; (C) Questions on KAP of Physicians around various aspects of APD management and PPI usage. Results : A total of 110 Physicians completed the survey. 92% observed stress as the most common risk factor; Obesity (46), Diabetes Mellitus (41%) and Cardiovascular Disease (33%) as the most frequent comorbidities, in APD. Almost all Physicians (99%) considered patient’s comorbidity important while choosing PPI. 84% participants felt that anticoagulants when co-prescribed with PPI have higher chance of drug-drug interactions. 60% ranked Rabeprazole in the top, in terms of safety and tolerability among PPIs. Conclusion: The present study mapped the awareness of Indian Physicians on APD, PPI usage, their adverse effects, drug-drug interactions; patient compliance and satisfaction with PPIs. These findings can be used to plan future interventions targeting HCPs, to ensure safe and appropriate use of PPIsen_US
dc.identifier.affiliationsDr Reddy’s Laboratories Limited, Ameerpet, Hyderabad, Telangana 500016en_US
dc.identifier.affiliationsMBBS, MHA, PGDMLE, Director/Cluster Head - Medical Affairsen_US
dc.identifier.affiliationsMBBS, MD, Medical Advisor and Corresponding Authoren_US
dc.identifier.affiliationsClinical Research Specialisten_US
dc.identifier.citationPebbili Kranthi Kiran, Pendurthi Bharadwaja, Bhagat Seema. A Prospective, Cross-sectional, Multicenter, Observational, Questionnaire-based Survey to assess the Knowledge, Awareness, Attitude and Practice of Physicians while Prescribing Proton Pump Inhibitor (PPI) Drugs for Acid Peptic Disease. Journal of The Indian Medical Association. 2022 Jul; 120(7): 67-72en_US
dc.identifier.issn0019-5847
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/216573
dc.languageenen_US
dc.publisherIndian Medical Associationen_US
dc.relation.issuenumber7en_US
dc.relation.volume120en_US
dc.source.urihttps://www.onlinejima.com/read_journals.php?article=986en_US
dc.subjectAcid peptide disorderen_US
dc.subjectAwarenessen_US
dc.subjectAttitudeen_US
dc.subjectKnowledgeen_US
dc.subjectProton pump inhibitoren_US
dc.titleA Prospective, Cross-sectional, Multicenter, Observational, Questionnaire-based Survey to assess the Knowledge, Awareness, Attitude and Practice of Physicians while Prescribing Proton Pump Inhibitor (PPI) Drugs for Acid Peptic Diseaseen_US
dc.typeJournal Articleen_US
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