Analysing the Shift in Prescribing Patterns: Sodium Glucose Co-transporter 2 Inhibitors, Dipeptidyl Peptidase 4 Inhibitors and Traditional Antidiabetic Drugs.

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dc.contributor.authorPavithran, Ven_US
dc.contributor.authorBalachandran, Pen_US
dc.contributor.authorSajeeth, CIen_US
dc.contributor.authorHariharan, Aen_US
dc.date.accessioned2025-08-13T10:00:10Z
dc.date.available2025-08-13T10:00:10Z
dc.date.issued2025-03
dc.description.abstractAbstract: India currently has around 77 million adults living with diabetes. Considering the growing impact of diabetesrelated complications, we aimed to compare the real-world prescribing patterns of sodium-glucose cotransporter-2 inhibitors, dipeptidyl peptidase-4 inhibitors and traditional antidiabetics. Using a cross-sectional study design, the prescribing pattern and factors influencing the utilisation of the antidiabetic drugs, categorised by the HbA1c status, were assessed using the chi-square test. Of 260 eligible adults with mean [SD] age, 63.7[12.4] years; 54.7% of male participants initiated treatment with sodium-glucose cotransporter-2 inhibitors (n=27) or a dipeptidyl peptidase-4 inhibitors (n=31). The use of newer antidiabetic agents has steadily increased, with a slightly higher initiation rate in those over 65 years (21.5%). No significant difference was observed based on age (p = 0.182) or gender (p = 0.9548). Prescriber speciality had a significant impact (p = 0.00038). Cardiologists showed the highest shift towards newer drugs (36.5%). Prescriptions of newer antidiabetics have shown an upward trend over time, indicating a shift in prescribing practices. However, this increase was limited. Further efforts are necessary to identify and address the barriers to underutilisation of these drugsen_US
dc.identifier.affiliationsResearch Scholar, Department of Pharmacy, Annamalai University, Annamalai Nagar, Tamil Nadu, India - 608002en_US
dc.identifier.affiliationsAssistant Professor, Department of Pharmacy, Annamalai University, Annamalai Nagar, Tamil Nadu, India - 608002en_US
dc.identifier.affiliationsProfessor and HOD, Department of Pharmacy, Grace college of Pharmacy, Palakkad, Kerala, India - 678004en_US
dc.identifier.affiliationsAssistant Professor, Department of General Medicine, Karuna Medical College and Hospital, Palakkad, Kerala, India - 678103en_US
dc.identifier.citationPavithran V, Balachandran P, Sajeeth CI, Hariharan A. Analysing the Shift in Prescribing Patterns: Sodium Glucose Co-transporter 2 Inhibitors, Dipeptidyl Peptidase 4 Inhibitors and Traditional Antidiabetic Drugs.. Online Journal of Health and Allied Sciences. 2025 Mar; 24(93): 1-6en_US
dc.identifier.issn0972-5997
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/252878
dc.languageenen_US
dc.publisherLight House Polyclinicen_US
dc.relation.issuenumber93en_US
dc.relation.volume24en_US
dc.source.urihttps://www.ojhas.org/issue93/2025-1-5.pdfen_US
dc.subjectDipeptidyl peptidase inhibitorsen_US
dc.subjectHbA1cen_US
dc.subjectPrescribing patternen_US
dc.subjectSodium glucose cotransporter 2 inhibitorsen_US
dc.subjectType 2 Diabetes Mellitus.en_US
dc.titleAnalysing the Shift in Prescribing Patterns: Sodium Glucose Co-transporter 2 Inhibitors, Dipeptidyl Peptidase 4 Inhibitors and Traditional Antidiabetic Drugs.en_US
dc.typeJournal Articleen_US
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