Efficacy of splinting and oral steroids in the treatment of carpal tunnel syndrome: a prospective randomized clinical and electrophysiological study.
dc.contributor.author | Mishra, Sanjay | en_US |
dc.contributor.author | Prabhakar, Sudesh | en_US |
dc.contributor.author | Lal, Vivek | en_US |
dc.contributor.author | Modi, Manish | en_US |
dc.contributor.author | Das, Chandi P | en_US |
dc.contributor.author | Khurana, Dheeraj | en_US |
dc.date.accessioned | 2006-09-29 | en_US |
dc.date.accessioned | 2009-06-03T11:04:02Z | |
dc.date.available | 2006-09-29 | en_US |
dc.date.available | 2009-06-03T11:04:02Z | |
dc.date.issued | 2006-09-29 | en_US |
dc.description.abstract | OBJECTIVE: To study the efficacy of splinting and oral steroids in the management of carpal tunnel syndrome (CTS). DESIGN: Prospective, randomized, open-label, clinical and electrophysiological study with 3-month follow-up. MATERIALS AND METHODS: Forty patients with CTS were randomly divided into splint group (N-20), wearing splint in neutral position for 4 weeks; and steroid group (N-20), who received oral prednisolone 20 mg/day for 2 weeks followed by 10 mg/day for 2 weeks. Clinical and electrophysiological evaluations were done at baseline and at 1-month and 3-month follow-up. Independent 't' test and paired 't' test were used for statistical analysis. OUTCOME MEASURES: Primary outcome measure was the symptom severity score and functional status score. Secondary outcome measures were median nerve sensory and motor distal latency and conduction velocity. RESULTS: At the end of 3 months, statistically significant improvement was seen in symptom severity score and functional status score in both groups (P<0.001). Median nerve sensory distal latency and conduction velocity also improved significantly in both the groups at 3 months. Improvement in motor distal latency was significant (P=0.001) at 3 months in steroid group, while insignificant improvement (P=0.139) was observed in splint group. On comparing the clinical and electrophysiological improvement between the two groups, except for the functional status score, there was no significant difference at 3-month follow-up. Improvement in functional status score was significantly more in steroid group (P=0.03). CONCLUSION: There was significant improvement in both groups, clinically as well as electrophysiologically, at 3 months. On comparing the efficacy of the two treatment methods, except for the functional status score, there was no significant difference between the two groups. | en_US |
dc.description.affiliation | Department of Neurology, PGIMER, Chandigarh, India. | en_US |
dc.identifier.citation | Mishra S, Prabhakar S, Lal V, Modi M, Das CP, Khurana D. Efficacy of splinting and oral steroids in the treatment of carpal tunnel syndrome: a prospective randomized clinical and electrophysiological study. Neurology India. 2006 Sep; 54(3): 286-90 | en_US |
dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/120642 | |
dc.language.iso | eng | en_US |
dc.source.uri | https://neurologyindia.com | en_US |
dc.subject.mesh | Administration, Oral | en_US |
dc.subject.mesh | Adult | en_US |
dc.subject.mesh | Anti-Inflammatory Agents --administration & dosage | en_US |
dc.subject.mesh | Carpal Tunnel Syndrome --drug therapy | en_US |
dc.subject.mesh | Drug Administration Schedule | en_US |
dc.subject.mesh | Electrophysiology | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Follow-Up Studies | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Middle Aged | en_US |
dc.subject.mesh | Neural Conduction --drug effects | en_US |
dc.subject.mesh | Prednisolone --administration & dosage | en_US |
dc.subject.mesh | Prospective Studies | en_US |
dc.subject.mesh | Reaction Time --drug effects | en_US |
dc.subject.mesh | Splints | en_US |
dc.subject.mesh | Time Factors | en_US |
dc.title | Efficacy of splinting and oral steroids in the treatment of carpal tunnel syndrome: a prospective randomized clinical and electrophysiological study. | en_US |
dc.type | Clinical Trial | en_US |
dc.type | Comparative Study | en_US |
dc.type | Journal Article | en_US |
dc.type | Randomized Controlled Trial | en_US |
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