Efficacy of splinting and oral steroids in the treatment of carpal tunnel syndrome: a prospective randomized clinical and electrophysiological study.

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dc.contributor.authorMishra, Sanjayen_US
dc.contributor.authorPrabhakar, Sudeshen_US
dc.contributor.authorLal, Viveken_US
dc.contributor.authorModi, Manishen_US
dc.contributor.authorDas, Chandi Pen_US
dc.contributor.authorKhurana, Dheerajen_US
dc.date.accessioned2006-09-29en_US
dc.date.accessioned2009-06-03T11:04:02Z
dc.date.available2006-09-29en_US
dc.date.available2009-06-03T11:04:02Z
dc.date.issued2006-09-29en_US
dc.description.abstractOBJECTIVE: To study the efficacy of splinting and oral steroids in the management of carpal tunnel syndrome (CTS). DESIGN: Prospective, randomized, open-label, clinical and electrophysiological study with 3-month follow-up. MATERIALS AND METHODS: Forty patients with CTS were randomly divided into splint group (N-20), wearing splint in neutral position for 4 weeks; and steroid group (N-20), who received oral prednisolone 20 mg/day for 2 weeks followed by 10 mg/day for 2 weeks. Clinical and electrophysiological evaluations were done at baseline and at 1-month and 3-month follow-up. Independent 't' test and paired 't' test were used for statistical analysis. OUTCOME MEASURES: Primary outcome measure was the symptom severity score and functional status score. Secondary outcome measures were median nerve sensory and motor distal latency and conduction velocity. RESULTS: At the end of 3 months, statistically significant improvement was seen in symptom severity score and functional status score in both groups (P<0.001). Median nerve sensory distal latency and conduction velocity also improved significantly in both the groups at 3 months. Improvement in motor distal latency was significant (P=0.001) at 3 months in steroid group, while insignificant improvement (P=0.139) was observed in splint group. On comparing the clinical and electrophysiological improvement between the two groups, except for the functional status score, there was no significant difference at 3-month follow-up. Improvement in functional status score was significantly more in steroid group (P=0.03). CONCLUSION: There was significant improvement in both groups, clinically as well as electrophysiologically, at 3 months. On comparing the efficacy of the two treatment methods, except for the functional status score, there was no significant difference between the two groups.en_US
dc.description.affiliationDepartment of Neurology, PGIMER, Chandigarh, India.en_US
dc.identifier.citationMishra S, Prabhakar S, Lal V, Modi M, Das CP, Khurana D. Efficacy of splinting and oral steroids in the treatment of carpal tunnel syndrome: a prospective randomized clinical and electrophysiological study. Neurology India. 2006 Sep; 54(3): 286-90en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/120642
dc.language.isoengen_US
dc.source.urihttps://neurologyindia.comen_US
dc.subject.meshAdministration, Oralen_US
dc.subject.meshAdulten_US
dc.subject.meshAnti-Inflammatory Agents --administration & dosageen_US
dc.subject.meshCarpal Tunnel Syndrome --drug therapyen_US
dc.subject.meshDrug Administration Scheduleen_US
dc.subject.meshElectrophysiologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshFollow-Up Studiesen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshNeural Conduction --drug effectsen_US
dc.subject.meshPrednisolone --administration & dosageen_US
dc.subject.meshProspective Studiesen_US
dc.subject.meshReaction Time --drug effectsen_US
dc.subject.meshSplintsen_US
dc.subject.meshTime Factorsen_US
dc.titleEfficacy of splinting and oral steroids in the treatment of carpal tunnel syndrome: a prospective randomized clinical and electrophysiological study.en_US
dc.typeClinical Trialen_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
dc.typeRandomized Controlled Trialen_US
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