Do All Children with Epilepsy have Behavioural Problems? A Multivariate Risk Factor Analysis.

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dc.contributor.authorNayak, Sen_US
dc.contributor.authorMathur, Men_US
dc.contributor.authorJain, AKen_US
dc.contributor.authorAgrawal, Hen_US
dc.contributor.authorBhargava, Ren_US
dc.contributor.authorGupta, Aen_US
dc.contributor.authorTripathi, Nen_US
dc.date.accessioned2025-08-13T10:00:11Z
dc.date.available2025-08-13T10:00:11Z
dc.date.issued2025-03
dc.description.abstractObjective: To identify independent risk factors and their odds ratio for behavioural problems in children with epilepsy. Methodology: This cross-sectional study involved children with epilepsy and matched controls. Epileptic children over 6 years old were selected through nonprobability sampling. Children of the same age and gender who visited the pediatric outpatient department for minor ailments served as controls. Behavior was assessed using the Child Behaviour Checklist (CBCL). Pearson’s correlation examined the relationship between behavioral problems, seizure onset age, frequency, and drug therapy duration. Multiple logistic regression after adjustment for confounders like age, gender, maternal education, and socioeconomic status was done. The independent risk factors for behavioral issues in epileptic children were identified and odds ratios calculated. Results: Among 100 children with epilepsy and 100 controls, 44% of epileptic children had behavioral problems versus 20% of controls (P=0.001). Behavioral scores were significantly higher in epileptic patients across all CBCL domains (P<0.001). Only the anxious/depressed domain showed differences between children receiving anti-epileptic monotherapy versus polytherapy (P=0.025). Longer seizure duration (OR=2.4), longer antiepileptic therapy duration (OR=1.8), and higher seizure frequency (OR=2.1) independently predicted behavioral problems in children with epilepsy. Type of seizures (generalized tonic-clonic versus partial) did not predict behaviour problems (OR=0.8). Conclusion: Behavioral problems are not universal among children with epilepsy. Increased seizure frequency and duration are independent risk factors for these issues.en_US
dc.identifier.affiliationsAssistant Professor, Department of Pediatrics, KMC Medical College, Maharajganj,273303, UP, Indiaen_US
dc.identifier.affiliationsAssociate Professor, Department of Psychiatry, Rama Medical College Hospital and Research Centre, Pilkhuwa, 245304, UP, Indiaen_US
dc.identifier.affiliationsAssistant Professor, Department of Pharmacology, NC Medical College & Hospital, Panipat, Haryanaen_US
dc.identifier.affiliationsAssistant Professor, Department of Pharmacology, GS Medical College, Pilkhuwa, 245304, UP, Indiaen_US
dc.identifier.affiliationsProfessor, Department of Ophthalmology, GS Medical College, Pilkhuwa, 245304, UP, Indiaen_US
dc.identifier.affiliationsAssistant Professor, Department of Pediatrics, MRA Medical College, Ambedkar Nagar, 223225, UP, Indiaen_US
dc.identifier.affiliationsSenior Resident, All India Institute of Medical Sciences, Gorakhpur, 273001, UP, India.en_US
dc.identifier.citationNayak S, Mathur M, Jain AK, Agrawal H, Bhargava R, Gupta A, Tripathi N. Do All Children with Epilepsy have Behavioural Problems? A Multivariate Risk Factor Analysis.. Online Journal of Health and Allied Sciences. 2025 Mar; 24(93): 1-4en_US
dc.identifier.issn0972-5997
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/252880
dc.languageenen_US
dc.publisherLight House Polyclinicen_US
dc.relation.issuenumber93en_US
dc.relation.volume24en_US
dc.source.urihttps://www.ojhas.org/issue93/2025-1-7.pdfen_US
dc.subjectBehavioral problemsen_US
dc.subjectChildrenen_US
dc.subjectEpilepsyen_US
dc.subjectlogistic regressionen_US
dc.subjectSeizure frequencyen_US
dc.titleDo All Children with Epilepsy have Behavioural Problems? A Multivariate Risk Factor Analysis.en_US
dc.typeJournal Articleen_US
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