Immunophenotype and cytochemical reactions of acute lymphoblastic leukemia in Thai children.

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Date
1992-01-01
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Abstract
The immunophenotypes of acute lymphoblastic leukemia (ALL) in 28 Thai children were studied by the APAAP technique using a panel of eight specific monoclonal antibodies: HLA-DR, CD 19, CALLA (CD 10), IgM, CD 7, CD 3, CD 4, and CD 8. Sixty-eight, 18, 3.5, 3.5, and 7 per cent were respectively shown to be common, null, pre-B, B, and mature thymocyte T subtypes. Cytochemical reactions (beta-glucuronidase, alpha naphthyl acetate esterase, and acid phosphatase) in this study could identify null, common, and T ALLs with confidence, and could be used in the process of ALL subtyping to reduce cost.
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Chotmaihet Thangphaet.
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Citation
Apibal S, Atichartakarn V, Salakit C, Nitiyanant P, Mahasandana C, Supradish P, Hathirat P. Immunophenotype and cytochemical reactions of acute lymphoblastic leukemia in Thai children. Journal of the Medical Association of Thailand. 1992 Jan; 75 Suppl 1(): 217-22