A Model Immunization Programme to Control Japanese Encephalitis in Viet Nam.

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dc.contributor.authorYen, Nguyen Thu
dc.contributor.authorLiu, Wei
dc.contributor.authorHanh, Hoang Duc
dc.contributor.authorChang, Na Yoon
dc.contributor.authorDuong, Tran Nhu
dc.contributor.authorGibbons, Robert V
dc.contributor.authorMarks, Florian
dc.contributor.authorThu, Nghiem Anh
dc.contributor.authorHong, Nguyen Minh
dc.contributor.authorPark, Jin Kyung
dc.contributor.authorTuan, Pham Anh
dc.contributor.authorNisalak, Ananda
dc.contributor.authorClemens, John D
dc.contributor.authorXu, Zhi-yi
dc.date.accessioned2016-02-25T07:29:01Z
dc.date.available2016-02-25T07:29:01Z
dc.date.issued2015-03
dc.description.abstractIn Viet Nam, an inactivated, mouse brain-derived vaccine for Japanese encephalitis (JE) has been given exclusively to ≤5 years old children in 3 paediatric doses since 1997. However, JE incidence remained high, especially among children aged 5-9 years. We conducted a model JE immunization programme to assess the feasibility and impact of JE vaccine administered to 1-9 year(s) children in 3 standard-dose regimen: paediatric doses for children aged <3 years and adult doses for those aged ≥3 years. Of the targeted children, 96.2% were immunized with ≥2 doses of the vaccine. Compared to the national immunization programme, JE incidence rate declined sharply in districts with the model programme (11.32 to 0.87 per 100,000 in pre- versus post-vaccination period). The rate of reduction was most significant in the 5-9 years age-group. We recommend a policy change to include 5-9 years old children in the catch-up immunization campaign and administer a 4th dose to those aged 5-9 years, who had received 3 doses of the vaccine during the first 2-3 years of life.en_US
dc.identifier.citationYen Nguyen Thu, Liu Wei, Hanh Hoang Duc, Chang Na Yoon, Duong Tran Nhu, Gibbons Robert V, Marks Florian, Thu Nghiem Anh, Hong Nguyen Minh, Park Jin Kyung, Tuan Pham Anh, Nisalak Ananda, Clemens John D, Xu Zhi-yi. A Model Immunization Programme to Control Japanese Encephalitis in Viet Nam. Journal of Health, Population and Nutrition. 2015 Mar; 33(1): 207-213.en_US
dc.identifier.issn1606-0997
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/174249
dc.language.isoenen_US
dc.source.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438663/?report=classicen_US
dc.subjectDemonstration projecten_US
dc.subjectEffectiveness studyen_US
dc.subjectImmunizationen_US
dc.subjectJapanese encephalitisen_US
dc.subjectVaccinesen_US
dc.titleA Model Immunization Programme to Control Japanese Encephalitis in Viet Nam.en_US
dc.typeArticleen_US
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