Design and development of Orally Disintegrating Tablets of Famotidine Prepared by Direct Compression Method Using Different Superdisintegrants.

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dc.contributor.authorKhinchi, Mahaveer Pr
dc.contributor.authorGupta, M K
dc.contributor.authorBhandari, Anil
dc.contributor.authorSharma, Natasha
dc.contributor.authorAgarwal, Dilip
dc.date.accessioned2014-05-12T05:28:35Z
dc.date.available2014-05-12T05:28:35Z
dc.date.issued2011-03
dc.description.abstractOrally disintegrating tablets (ODT) are gaining popularity over conventional tablets due to their convenience in administration and suitability for patients having dysphagia. Moreover no water is required for swallowing the tablets and hence suitable for geriatric, pediatric and traveling patients. Super disintegrants (such as Ac-Di-Sol, Crospovidone, sodium starch glycolate), Diluents (Dibasic calcium phosphate) along with sweetening agent (aspartame) were used in the formulation of tablets. The tablets were evaluated for hardness, friability, water absorption ratio, in-vitro disintegration time (DT), in-vitro disintegration time in oral cavity and in vitro drug release. Using the same excipients, the tablets were prepared by direct compression and were evaluated in the similar way. Maximum drug release and minimum DT were observed with Crospovidone excipient prepared by direct compression.en_US
dc.identifier.citationKhinchi Mahaveer Pr, Gupta M K, Bhandari Anil, Sharma Natasha, Agarwal Dilip. Design and development of Orally Disintegrating Tablets of Famotidine Prepared by Direct Compression Method Using Different Superdisintegrants. Journal of Applied Pharmaceutical Science. 2011 Mar; 1(1): 50-58.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/150738
dc.language.isoenen_US
dc.source.urihttps://www.japsonline.com/counter.php?aid=11en_US
dc.subjectOrally disintegrating tabletsen_US
dc.subjectAc-Di-Solen_US
dc.subjectCrospovidoneen_US
dc.subjectDibasic calcium phosphateen_US
dc.titleDesign and development of Orally Disintegrating Tablets of Famotidine Prepared by Direct Compression Method Using Different Superdisintegrants.en_US
dc.typeArticleen_US
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