Investigating the therapeutic potential of venom-derived compounds for the management of Alzheimer's disease: a comprehensive review

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dc.contributor.authorAimenen_US
dc.contributor.authorGul, MHen_US
dc.contributor.authorSohail, Ren_US
dc.contributor.authorPahwani, Ren_US
dc.contributor.authorSiddiqui, ARen_US
dc.contributor.authorNadeem, Sen_US
dc.contributor.authorWardak, ABen_US
dc.contributor.authorNazir, Hen_US
dc.contributor.authorAhmad, Sen_US
dc.contributor.authorAhmed, A.en_US
dc.date.accessioned2025-05-12T08:25:53Z
dc.date.available2025-05-12T08:25:53Z
dc.date.issued2024-09
dc.description.abstractAlzheimer’s disease is a comprehensive clinical syndrome featuring cognitive, emotional, and volitional function deterioration. Treatment strategies for Alzheimer's disease involve a mix of pharmacological and non-pharmacological approaches. Current treatments focus on palliative care with limited impact on the disease course. Venom-derived substances, known for their neuroactive properties, have emerged as a novel approach to Alzheimer's treatment. Our team conducted a thorough search for electronic literature related to therapeutic venom-derived substances efficacy in Alzheimer’s disease in different databases, including Medline, PubMed, Google Scholar, and Psych INFO, up to May 2024. In this article, the therapeutic effects of various venom-derived substances effects in Alzheimer’s disease are discussed. Various substances grant anti-inflammatory and anti-oxidant effects. The clinical application of venom-derived therapy is still a long way ahead, still, researchers believe that the ongoing work will eventually allow its compounds to be considered definitive candidates in various therapies in upcoming years.en_US
dc.identifier.affiliationsDepartment of Medicine, BahawalVictoria Hospital, Pakistanen_US
dc.identifier.affiliationsDepartment of Medicine, Lady Reading Hospital, Peshawar, Pakistanen_US
dc.identifier.affiliationsDepartment of Medicine, Quaid-Azam Medical College Bahawalpur, Pakistanen_US
dc.identifier.affiliationsDepartment of Medicine, Jinnah Sindh Medical University Karachi, Pakistanen_US
dc.identifier.affiliationsDepartment of Medicine, Liaquat University of Medical and Health Sciences,Jamshoro, Sindh, Pakistanen_US
dc.identifier.affiliationsDepartment of Medicine, Multan Institute of Cardiology, Pakistanen_US
dc.identifier.affiliationsDepartment of Medicine, Razia Bahlol Hospital, Afghanistanen_US
dc.identifier.affiliationsDepartment of Medicine, Hayatabad Medical Complex, Pakistanen_US
dc.identifier.affiliationsDepartment of Medicine, Khyber Medical College, Peshawar, Pakistanen_US
dc.identifier.affiliationsDepartment of Medicine, Cork University Hospital, Cork, Irelanden_US
dc.identifier.citationAimen, Gul MH, Sohail R, Pahwani R, Siddiqui AR, Nadeem S, Wardak AB, Nazir H, Ahmad S, Ahmed A.. Investigating the therapeutic potential of venom-derived compounds for the management of Alzheimer's disease: a comprehensive review . International Journal of Scientific Reports. 2024 Sep; 10(9): 340-345en_US
dc.identifier.issn2454-2156
dc.identifier.issn2454-2164
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/246989
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber9en_US
dc.relation.volume10en_US
dc.source.urihttps://doi.org/10.18203/issn.2454-2156.IntJSciRep20242372en_US
dc.subjectAlzheimer’s diseaseen_US
dc.subjectPharmacological treatmenten_US
dc.subjectBee venomsen_US
dc.subjectVenom-derived substancesen_US
dc.subjectTherapeutic effectsen_US
dc.titleInvestigating the therapeutic potential of venom-derived compounds for the management of Alzheimer's disease: a comprehensive reviewen_US
dc.typeJournal Articleen_US
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