Discrete subvalvular aortic stenosis.

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dc.contributor.authorSharma, B Den_US
dc.contributor.authorMittal, Sen_US
dc.contributor.authorKasliwal, R Ren_US
dc.contributor.authorTrehan, Nen_US
dc.contributor.authorKohli, Ven_US
dc.date.accessioned2000-11-20en_US
dc.date.accessioned2009-05-31T02:16:09Z
dc.date.available2000-11-20en_US
dc.date.available2009-05-31T02:16:09Z
dc.date.issued2000-11-20en_US
dc.description37 references.en_US
dc.description.abstractDiscrete Subaortic Stenosis is one of the many lesions responsible for left ventricular outflow tract (LVOT) obstruction. It may present as in an isolated from as membranous or fibromuscular ring below the aortic valve or in association with other congenital anamolies such as VSD, PDA, coarctation of aorta, hypoplastic aortic annulus, double chamber right ventricle among others. The condition is rarely diagnosed antenataly or in infancy but often manifests in the first decade of life with features of progressive LVOT obstruction, LV hypertrophy and dysfunction aortic regurgitation due to damage to the aortic cusps because of the jet from the subaortic narrowing which may also render the aortic valve prone to infective endocarditis. Interaction of genetic predisposition and morphologically deformed long and narrow LVOT cause rheological abnormalities and increased shear stress in the region of subaortic stenosis and seem to be the main etiological factor alongwith poorly defined role of more extensive but subtle changes in the LV endocardium. Condition can be easily diagnosed by cross-sectional and Doppler echocardiography and confirmed by demonstrating a pressure gradient below aortic valve on cardiac catheterisation and LV angiography. Surgical membranectomy alongwith myotomy or myomectomy remain the mainstay of treatment but long term results are not satisfactory as there is a high rate of recurrences requiring reoperations. A close follow up with serial echocardiographic examinations is very helpful in early detection of subaortic obstruction in patients who have so called functional murmurs in the childhood.en_US
dc.description.affiliationEscorts Heart Institute and Research Centre, Okhla Road, New Delhi 110 025.en_US
dc.identifier.citationSharma BD, Mittal S, Kasliwal RR, Trehan N, Kohli V. Discrete subvalvular aortic stenosis. Journal of the Association of Physicians of India. 2000 Nov; 48(11): 1103-6en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/92895
dc.language.isoengen_US
dc.source.urihttps://www.japi.orgen_US
dc.subject.meshAngiographyen_US
dc.subject.meshAortic Valve Stenosis --complicationsen_US
dc.subject.meshEchocardiography, Doppleren_US
dc.subject.meshFemaleen_US
dc.subject.meshHeart Catheterizationen_US
dc.subject.meshHeart Valve Prosthesisen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshPrognosisen_US
dc.subject.meshTreatment Outcomeen_US
dc.subject.meshVentricular Outflow Obstruction --diagnosisen_US
dc.titleDiscrete subvalvular aortic stenosis.en_US
dc.typeJournal Articleen_US
dc.typeReviewen_US
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