Breast cancer in a tertiary cancer center in India - An audit, with outcome analysis

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dc.contributor.authorNair, Nitaen_US
dc.contributor.authorShet, Tanujaen_US
dc.contributor.authorParmar, Vanien_US
dc.contributor.authorHavaldar, Rohinien_US
dc.contributor.authorGupta, Sudeepen_US
dc.contributor.authorBudrukkar, Ashwinien_US
dc.contributor.authorSarin, Rajiven_US
dc.contributor.authorThakur, Meenakshien_US
dc.contributor.authorDesai, Sangeetaen_US
dc.contributor.authorYadav, Prabhaen_US
dc.contributor.authorjalali, Rakeshen_US
dc.contributor.authorGulia, Seemaen_US
dc.contributor.authorWadasadawala, Tabassumen_US
dc.contributor.authorGosh, Jayaen_US
dc.contributor.authorBajpai, Jyotien_US
dc.contributor.authorKembhavi, Seemaen_US
dc.contributor.authorPatil, Asawarien_US
dc.contributor.authorJoshi, Shalakaen_US
dc.contributor.authorPopat, Palaken_US
dc.contributor.authorRangarajan, Venkateshen_US
dc.contributor.authorShah, Snehaen_US
dc.contributor.authorVanmali, Vaibhaven_US
dc.contributor.authorSiddiqui, Shabinaen_US
dc.contributor.authorMittra, Indraneelen_US
dc.contributor.authorBadwe, Rajendraen_US
dc.date.accessioned2020-01-02T06:28:00Z
dc.date.available2020-01-02T06:28:00Z
dc.date.issued2018-01
dc.description.abstractBackground: Surgery is the mainstay in the management of thyroid cancer. Surgical outcomes need to be tempered against the excellent prognosis of the disease. Aims: This study aims to study the surgical outcomes including the 30-day morbidity and 5-year survival of thyroid cancer patients. Settings and Design: Retrospective analysis of a prospectively maintained surgical database in a tertiary cancer center in India. Materials and Methods: We analyzed 221 surgically treated patients in the year 2012. Statistical Analysis: Used IBM SPSS 24.0 (Armonk, NY) with p < 0.05. Results: The median age was 40 years with predominantly papillary thyroid carcinoma (55%). Localized disease in 47% of cases, locoregional disease in 42.5% and distant metastasis in 10.2% of cases at presentation was noted. Treatment naïve patients were 71% and revision surgeries were done in 29% patients. Extended thyroidectomy constituted 11% of the surgeries. Temporary hypocalcemia was seen in 30.8% of patients, 5% requiring intravenous calcium supplementation. Vocal cord palsy as per nerve at risk and chyle leak were seen in 4.5% and 3.1%, respectively. Aggressive histology, extended thyroidectomy, and inadvertent parathyroidectomy were significant factors associated with complications. Five year estimated overall survival with median follow-up of 50 months was 98%, and event-free survival was 84.8%. Advanced age, distant metastasis at presentation and aggressive histology connoted poor outcomes. Conclusion: Thyroid cancer, irrespective of the extent of disease, has good prognosis. Aggressive histology, the extent of thyroid surgery, distant metastasis and age are important factors, which should be factored in the algorithm of thyroid cancer management.en_US
dc.identifier.affiliationsDepartment of Surgical Oncology, Tata Memorial Hospital, Mumbai, Maharashtra, Indiaen_US
dc.identifier.affiliationsDepartment of Pathology, Tata Memorial Hospital, Mumbai, Maharashtra, Indiaen_US
dc.identifier.affiliationsClinical Research Secretariat, Tata Memorial Hospital, Mumbai, Maharashtra, Indiaen_US
dc.identifier.affiliationsDepartment of Medical oncology, Tata Memorial Hospital, Mumbai, Maharashtra, Indiaen_US
dc.identifier.affiliationsDepartment of Radiation Oncology, Tata Memorial Hospital, Mumbai, Maharashtra, Indiaen_US
dc.identifier.affiliationsI/C Cancer Genetic Unit, Tata Memorial Hospital, Mumbai, Maharashtra, Indiaen_US
dc.identifier.affiliationsDepartment of Radiodiagnosis, Tata Memorial Hospital, Mumbai, Maharashtra, Indiaen_US
dc.identifier.affiliationsDepartment of Nuclear Medicine and Molecular Imaging, Tata Memorial Hospital, Mumbai, Maharashtra, Indiaen_US
dc.identifier.citationNair Nita, Shet Tanuja, Parmar Vani, Havaldar Rohini, Gupta Sudeep, Budrukkar Ashwini, Sarin Rajiv, Thakur Meenakshi, Desai Sangeeta, Yadav Prabha, jalali Rakesh, Gulia Seema, Wadasadawala Tabassum, Gosh Jaya, Bajpai Jyoti, Kembhavi Seema, Patil Asawari, Joshi Shalaka, Popat Palak, Rangarajan Venkatesh, Shah Sneha, Vanmali Vaibhav, Siddiqui Shabina, Mittra Indraneel, Badwe Rajendra. Breast cancer in a tertiary cancer center in India - An audit, with outcome analysis. Indian Journal of Cancer. 2018 Jan; 55(1): 16-22en_US
dc.identifier.issn0019-509X
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/190350
dc.languageenen_US
dc.publisherIndian Cancer Societyen_US
dc.relation.issuenumber1en_US
dc.relation.volume55en_US
dc.source.urihttps://dx.doi.org//10.4103/ijc.IJC_484_17en_US
dc.titleBreast cancer in a tertiary cancer center in India - An audit, with outcome analysisen_US
dc.typeJournal Articleen_US
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