Recent advances in hepatorenal syndrome.

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dc.contributor.authorArroyo, Vicenteen_US
dc.contributor.authorTorre, Aldoen_US
dc.contributor.authorGuevara, Mónicaen_US
dc.date.accessioned2005-01-25en_US
dc.date.accessioned2009-06-04T04:28:47Z
dc.date.available2005-01-25en_US
dc.date.available2009-06-04T04:28:47Z
dc.date.issued2005-01-25en_US
dc.description70 references.en_US
dc.description.abstractHepatorenal syndrome is a common complication of advanced cirrhosis, characterized by renal failure and major disturbances in circulatory function. Renal failure is caused by intense vasoconstriction of the renal circulation. The syndrome is probably the final consequence of extreme underfilling of the arterial circulation secondary to arterial vasodilatation in the splanchninc vascular bed. The diagnosis of HRS is currently based on the exclusion of other causes of renal failure. The prognosis is very poor, particularly when there is rapidly progressive renal failure (type 1). Liver transplantation is the best option in patients without contraindications to the procedure, but it is not always possible owing to the short survival expectancy. Therapies introduced during the past few years, such a vasoconstrictor drugs (vasopressin analogues, mu-adrenergic agonist) or the transjugular intrahepatic portosystemic shunt, are effective in improving renal function. Nevertheless, liver transplantation should still be done in suitable patients even after improvement of renal function because the outcome of HRS is poor.en_US
dc.description.affiliationLiver Unit, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi-Sunyer, University of Barcelona School of Medicine, Barcelona, Catalunya, Spain. arroyo@medicina.ub.esen_US
dc.identifier.citationArroyo V, Torre A, Guevara M. Recent advances in hepatorenal syndrome. Tropical Gastroenterology. 2005 Jan-Mar; 26(1): 13-20en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/124949
dc.language.isoengen_US
dc.source.urihttps://www.tropicalgastro.comen_US
dc.subject.meshClinical Trials as Topicen_US
dc.subject.meshHepatorenal Syndrome --diagnosisen_US
dc.subject.meshHumansen_US
dc.subject.meshPrognosisen_US
dc.titleRecent advances in hepatorenal syndrome.en_US
dc.typeJournal Articleen_US
dc.typeReviewen_US
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