Epidemiology & antibiograms of Vibrio cholerae isolates from a tertiary care hospital in Chandigarh, north India.

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dc.contributor.authorChander, Jagdish
dc.contributor.authorKaistha, Neelam
dc.contributor.authorGupta, Varsha
dc.contributor.authorMehta, Manjula
dc.contributor.authorSingla, Nidhi
dc.contributor.authorDeep, Antariksh
dc.contributor.authorSarkar, B L
dc.date.accessioned2011-12-13T09:53:42Z
dc.date.available2011-12-13T09:53:42Z
dc.date.issued2009-05
dc.description.abstractBackground & objectives: Cholera is endemic in Chandigarh and its surrounding areas. This retrospective study was undertaken over a period of nine years (January 1999-December 2007) from a tertiary care hospital in north India to understand the changing epidemiology aspects and antibiotic resistance patterns in Vibrio cholerae isolates. Methods: A total of 277 isolates of V. cholerae were included in the study. V. cholerae was identifi ed by standard microbiological procedures. Antibiotic sensitivity testing was performed by disc diffusion method and isolates phage typed. Results: All the isolates were identifi ed as V. cholerae O1 biotype El Tor serotype Ogawa; phage 27 was the predominant type. Men were more commonly affected with maximum number in the age group 0-5 yr. Majority of the isolates were resistant to furazolidone but sensitive to gentamicin and cefotaxime. Resistance pattern to amoxycillin was variable. Three isolates were found to be resistant to ciprofl oxacin. All the patients presented during June-October coinciding with the monsoon season and a majority were from suburbs. Interpretation & conclusions: The emergence of resistance amongst V. cholerae especially towards ciprofl oxacin may signifi cantly infl uence the control strategies in future outbreaks. Phage 27 remained the predominant type in all the years. Continuous surveillance with regard to drug resistance, early detection and a strong regional commitment may help contain the disease.en_US
dc.identifier.citationChander Jagdish, Kaistha Neelam, Gupta Varsha, Mehta Manjula, Singla Nidhi, Deep Antariksh, Sarkar B L. Epidemiology & antibiograms of Vibrio cholerae isolates from a tertiary care hospital in Chandigarh, north India. Indian Journal of Medical Research. 2009 May; 129(5): 613-617.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/135834
dc.language.isoenen_US
dc.source.urihttps://icmr.nic.in/ijmr/2009/may/0522.pdfen_US
dc.subjectCholeraen_US
dc.subjectdrug resistanceen_US
dc.subjectepidemiologyen_US
dc.subjectOgawaen_US
dc.subjectphage typeen_US
dc.subjectVibrio choleraeen_US
dc.titleEpidemiology & antibiograms of Vibrio cholerae isolates from a tertiary care hospital in Chandigarh, north India.en_US
dc.typeArticleen_US
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