Radiological manifestations of splenic tuberculosis: a 23-patient case series from India.

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dc.contributor.authorSharma, S Ken_US
dc.contributor.authorSmith-Rohrberg, Duncanen_US
dc.contributor.authorTahir, Mohammaden_US
dc.contributor.authorMohan, Alladien_US
dc.contributor.authorSeith, Ashuen_US
dc.date.accessioned2007-05-24en_US
dc.date.accessioned2009-05-27T07:59:55Z
dc.date.available2007-05-24en_US
dc.date.available2009-05-27T07:59:55Z
dc.date.issued2007-05-24en_US
dc.description.abstractBACKGROUND & OBJECTIVE: Splenic tuberculosis (TB) is a less common but important manifestation of abdominal TB, especially in India and other developing countries. Its prevalence is increasing with the epidemic of HIV-TB co-infection and subsequent rise in extrapulmonary TB. The range of radiological manifestations of splenic TB is poorly described. Here, we review the ultrasonographic and computed tomographic (CT) images of 23 cases from two large tertiary care centers in India. METHODS: Radiographic images, ultrasonographic in all cases and CT in selected cases, were retrospectively analyzed in a series of 23 patients presenting to two large tertiary care centers in India, with suspected TB and with splenomegaly on physical examination. Images were assessed at baseline and when available following anti-tuberculosis therapy. RESULTS: The ultrasound and CT findings included, in order of most common: single or multiple hypoechoic focal lesions, splenic abscess, calcifications (on CT), and isolated splenomegaly. Five of the six patients with findings of isolated splenomegaly on ultrasound were found to have lesions on CT. INTERPRETATION & CONCLUSION: Ultrasonography of the spleen is an affordable, non-invasive imaging modality, which can be helpful in diagnosis of splenic TB and assessment of therapeutic response. Proper use of this imaging modality in splenic TB should help avoid unnecessary CT imaging or invasive procedures. However, this technique is operator-dependent, and, when extensive intraabdominal involvement is suspected, or the diagnosis is unclear, CT may be necessary.en_US
dc.description.affiliationDepartment of Medicine, All India Institute of Medical Sciences, New Delhi. sksharma@aiims.ac.inen_US
dc.identifier.citationSharma SK, Smith-Rohrberg D, Tahir M, Mohan A, Seith A. Radiological manifestations of splenic tuberculosis: a 23-patient case series from India. Indian Journal of Medical Research. 2007 May; 125(5): 669-78en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/22863
dc.language.isoengen_US
dc.source.urihttps://icmr.nic.in/ijmr/ijmr.htmen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshTomography, X-Ray Computeden_US
dc.subject.meshTuberculosis, Splenic --radiographyen_US
dc.titleRadiological manifestations of splenic tuberculosis: a 23-patient case series from India.en_US
dc.typeJournal Articleen_US
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