Evaluation Of Anticonvulsant Activity Of Cow Urine Betel Vine Extract In Mice
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Date
2019-12
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Publisher
Bimonthly published online Journal
Abstract
The present study was designed to investigate the anticonvulsant activity of Cowurine betel vine extract in rats. Anticonvulsant activity was performed by using the two modelsMaximal Electric Shock (MES) induced convulsions and Pentylene tetrazole (PTZ) inducedconvulsions. The animals were fed with Cow urine betel vine extract at the dose of 250 and500mg/kg b.w orally for a period of 14 days. The pretreated extract reduced the convulsions ina dose dependent manner which was determined by taking the duration of flexion, extensor,clonus and stupor phase and Percentage of inhibition of seizures relative to controls wascalculated.
Description
Keywords
Anticonvulsant activity, MES, PTZ, Cow urine betel vine extract
Citation
B. A Sowmya, M.N Sunil Kumar. Evaluation Of Anticonvulsant Activity Of Cow Urine Betel Vine Extract In Mice. International Journal of Pharmaceutical Research and Bioscience (IJPRBS). 2019 Dec; 8(6): 1-11