Chemical characterization of an Ayurvedic herbo-mineral preparation- Mahalaxmivilas Rasa

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dc.contributor.authorSrikanth, N.en_US
dc.contributor.authorSingh, A.en_US
dc.contributor.authorOta, S.en_US
dc.contributor.authorSreedhar, B.en_US
dc.contributor.authorGaliben_US
dc.contributor.authorDhiman, K.S.en_US
dc.date.accessioned2020-11-18T10:11:56Z
dc.date.available2020-11-18T10:11:56Z
dc.date.issued2019-10
dc.description.abstractBackground: To protect the massive trust of patient in Ayurveda, a need aroused for the researches toascertain the quality, safety & efficacy of herbo-mineral preparations on scientific lines. The rasa-aushadhis are having qualities such as instant effectiveness, requirement in very small dosage and ampletherapeutic utility. Mahalaxmi Vilas Rasa [AFI, 20:27] has been used for treatment of a variety of ailmentssince time immemorial.Objective: To prepare Mahalaxmi Vilas Rasa as per standard operating procedures (SoPs) mentioned inclassical text and to characterize it chemically using modern analytical techniques.Materials and Methods: The drug (Mahalaxmi Vilas Rasa) in three batches was prepared in GMP certifiedpharmacy. Physico-chemical analysis, HPTLC, Assay of elements by AAS & ICP-AES were carried out as perAyurvedic Pharmacopoeia of India. Powder X-ray diffraction (XRD) was conducted using Rigaku UltimaIV X-ray diffractometer.Results: The elemental analysis shown the presence of Mercury, Sulphur, Calcium, Copper, Gold, Iron &Tin etc. and HPTLC revealed presence of organic constituents from plant material. The XRD had indicatedthat prepared drug contained free sulphur, cinnabar (mercury sulphide added as Kajjali), cassiterite (tinoxide, Vanga Bhasma), orpiment (Hartal, arsenic III sulphide) and mica (Leucite/ Zeolite, Abhrak Bhasma).The drug was also tested for residual pesticide and microbiological contamination which were foundwithin permissible limits.Conclusion: Classical pharmaceutical procedures of Mahalaxmi Vilas Rasa showed converting the macroelements into therapeutically effective medicines of micro form. Standards laid down in this study certainlyutilized as an important tool for standardization and quality assurance of this herbo-mineral formulation.© 2018 Transdisciplinary University, Bangalore and World Ayurveda Foundation. Publishing Services byElsevier B.V. This is an open access article under the CC BY-NC-ND license (https://creativecommons.org/licenses/by-nc-nd/4.0/).en_US
dc.identifier.affiliationsCentral Council for Research in Ayurvedic Sciences, 61-65, Institutional Area, Opp. D-Block, Janakpuri, New Delhi, Indiaen_US
dc.identifier.affiliationsCentral Council for Research in Ayurvedic Sciences, 61-65, Institutional Area, Opp. D-Block, Janakpuri, New Delhi, Indiaen_US
dc.identifier.affiliationsCentral Council for Research in Ayurvedic Sciences, 61-65, Institutional Area, Opp. D-Block, Janakpuri, New Delhi, Indiaen_US
dc.identifier.affiliationsIndian Institute of Chemical Technology, Uppal Road, Tarnaka, Hyderabad, Indiaen_US
dc.identifier.affiliationsAll India Institute of Ayurveda, Sarita Vihar, New Delhi, Indiaen_US
dc.identifier.affiliationsCentral Council for Research in Ayurvedic Sciences, 61-65, Institutional Area, Opp. D-Block, Janakpuri, New Delhi, Indiaen_US
dc.identifier.citationSrikanth N., Singh A., Ota S., Sreedhar B., Galib, Dhiman K.S.. Chemical characterization of an Ayurvedic herbo-mineral preparation- Mahalaxmivilas Rasa. Journal of Ayurveda and Integrative Medicine. 2019 Oct; 10(4): 262-268en_US
dc.identifier.issn0975-9476
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/214090
dc.languageenen_US
dc.publisherElsevieren_US
dc.relation.issuenumber4en_US
dc.relation.volume10en_US
dc.source.urihttps://dx.doi.org//10.1016/j.jaim.2018.01.002en_US
dc.titleChemical characterization of an Ayurvedic herbo-mineral preparation- Mahalaxmivilas Rasaen_US
dc.typeJournal Articleen_US
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