Serum Lipids and Diabetic Retinopathy in Newly Diagnosed Type 2 Diabetic Subjects.
Loading...
Date
2011-07
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Background: Diabetic retinopathy is the commonest and usually the first observable vascular
complication of diabetes mellitus. Along with hyperglycaemia, dyslipidaemia is a contributing
factor for the occurrence of diabetic retinopathy. It is postulated that dyslipidaemia results in
formation of hard exudate by increasing blood viscosity and altering the fibrinolytic system. A
case control study was carried out in the department of Biochemistry, Bangabandhu Sheikh
Mujib Medical University, Dhaka during the period of January 2006 to December 2007 to
evaluate the serum lipid profile in newly diagnosed type 2 diabetic subjects with diabetic
retinopathy. Materials and Methods: Total 85 newly diagnosed type 2 diabetic subjects were
included in this study, 40 were cases having retinopathy and 45 were age and sex matched
controls without retinopathy. Serum triglyceride (TG), total cholesterol (TC), low density
lipoprotein cholesterol (LDL-C) and high density lipoprotein cholesterol (HDL-C) were
compared between cases and controls. Unpaired t-test and chi-square test were done between
groups as tests of significance. Results: All the parameters of lipid profile showed
dyslipidaemic trend both in cases and controls. In the cases TG was significantly higher and
HDL-C was significantly lower than that of controls (p < 0.05) whereas no significant
difference was found between cases and controls with respect to serum TC and LDL-C.
Conclusion: It can be concluded that high TG and low HDL-C are associated with diabetic
retinopathy in newly diagnosed type 2 diabetes.
Description
Keywords
Lipid profile, Dyslipidaemia, Diabetic retinopathy
Citation
Rahman Md Rezwanur, Arslan M Iqbal, Hoque Md Mozammel, Mollah Forhadul Hoque, Shermin Shahana. Serum Lipids and Diabetic Retinopathy in Newly Diagnosed Type 2 Diabetic Subjects. Journal of Enam Medical College. 2011 July; 1(2): 63-66.