The cytosol receptors for progesterone in the different parts of rabbit fallopian tube and uterus during ovum transport.
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Date
1980-12
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Abstract
Progesterone receptors were determined in the cytosol from the ampulla, ampullaryisthmic
junction and isthmus of rabbit fallopian tube and uterus of estrus and pregnant rabbits.
The receptor levels when compared among its various anatomical segments, were the same in
ampulla, isthums and uterus but maximum in ampullary-isthmic junction. Significant differences
were observed in mated animals at 14, 24, 34, 48, 70 and 144 h after coitus. The receptor
concentrations in portions of the fallopian tube showed no significant change between 14 and 24 h
after coitus, except for a decrease in ampullary-isthmic junction at 24 h. At 34 h the concentration
of receptor further decreased in all parts of the tube. At 48 and 70 h after coitus, receptor
concentrations decreased gradually in ampulla and ampullary-isthmic junction, while isthmus
showed a gradual increase. At 144 h, the receptor concentration showed no further change in
ampulla and ampullary-isthmic junction; however, isthmus showed a decline. The uterine
receptor concentration declined steadily from estrus till 70 h after coitus, however, it was
increased at 144 h. The dissociation constant (Kd) of cytosol receptor in all the tissues at estrus
and during early pregnancy was found similar. The implications of these changes in relation to
the normal ovum transport have been correlated in this paper.
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Keywords
Progesterone, receptors, fallopian tube, ovum transport, rabbit
Citation
Puri Raj K, Roy S K. The cytosol receptors for progesterone in the different parts of rabbit fallopian tube and uterus during ovum transport. Journal of Biosciences. 1980 Dec; 2(4): 355-360.