Prevalence of central nervous system cryptococcosis in human immunodeficiency virus reactive hospitalized patients.

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dc.contributor.authorLakshmi, Ven_US
dc.contributor.authorSudha, Ten_US
dc.contributor.authorTeja, V Den_US
dc.contributor.authorUmabala, Pen_US
dc.date.accessioned2007-04-22en_US
dc.date.accessioned2009-05-28T09:13:34Z
dc.date.available2007-04-22en_US
dc.date.available2009-05-28T09:13:34Z
dc.date.issued2007-04-22en_US
dc.description.abstractCentral nervous system cryptococcosis is an important cause of mortality among human immunodeficiency virus (HIV) reactive patients. A retrospective study was conducted on a total of 1,863 HIV reactive hospitalized patients suspected of cryptococcal meningitis. Three hundred and fifty-nine cerebrospinal fluid specimens of these cases were screened for various cryptococcal investigations. Thirty-nine out of 359 (10.86%) showed a definite diagnosis of cryptococcosis with a mortality rate of 25.64%. Prevalence of cryptococcal meningitis in the total HIV reactive cohort was 2.09%. Concurrent cryptococcal meningitis and tuberculosis was seen in 33.3% cases. A high index of clinical suspicion and routine mycological surveillance is required to help an early diagnosis and appropriate therapy, as majority of patients respond well to therapy if treated early.en_US
dc.description.affiliationDepartment of Microbiology, Nizam's Institute of Medical Sciences, Hyderabad - 500 082, India. lgorthi@hotmail.comen_US
dc.identifier.citationLakshmi V, Sudha T, Teja VD, Umabala P. Prevalence of central nervous system cryptococcosis in human immunodeficiency virus reactive hospitalized patients. Indian Journal of Medical Microbiology. 2007 Apr; 25(2): 146-9en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/53614
dc.language.isoengen_US
dc.source.urihttps://www.ijmm.orgen_US
dc.subject.meshAIDS-Related Opportunistic Infections --epidemiologyen_US
dc.subject.meshCerebrospinal Fluid --microbiologyen_US
dc.subject.meshHIV Infections --complicationsen_US
dc.subject.meshHIV-1en_US
dc.subject.meshHospitalizationen_US
dc.subject.meshHumansen_US
dc.subject.meshIndia --epidemiologyen_US
dc.subject.meshMeningitis, Cryptococcal --epidemiologyen_US
dc.subject.meshPrevalenceen_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshTuberculosis --epidemiologyen_US
dc.titlePrevalence of central nervous system cryptococcosis in human immunodeficiency virus reactive hospitalized patients.en_US
dc.typeJournal Articleen_US
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