Ependymosarcoma presenting as recurrence in a primary left parieto-occipital ependymoma

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dc.contributor.authorPrasad, Pallavien_US
dc.contributor.authorBaranwal, Harshitaen_US
dc.contributor.authorGupta, Neelimaen_US
dc.date.accessioned2025-08-13T11:40:48Z
dc.date.available2025-08-13T11:40:48Z
dc.date.issued2025-06
dc.description.abstractEpendymomas are glial tumors that may arise from the supratentorial, posterior fossa, and spinal compartments. Conventional ependymomas belong to WHO grade 2. Gliosarcoma is described as a variant of IDH?wildtype glioblastoma, comprising a biphasic tissue pattern with alternating areas displaying glial and mesenchymal differentiation. It may develop in an ependymoma, in addition to astrocytomas. This sarcomatous transformation portends a more aggressive behavior; hence, this entity should be kept in mind during the management of lesions with atypical imaging features on diagnosis. We report a rare presentation of ependymosarcoma presenting nearly 1.5 years later after the excision of a conventional ependymoma in a young female. Upon presentation as recurrence, the patient developed symptoms and atypical imaging findings. Histopathological and immunohistochemical examination of the excised tumor specimens revealed sarcomatous change occurring in an operated prior conventional ependymoma.en_US
dc.identifier.affiliationsDepartment of Pathology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Pathology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Pathology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, Indiaen_US
dc.identifier.citationPrasad Pallavi, Baranwal Harshita, Gupta Neelima . Ependymosarcoma presenting as recurrence in a primary left parieto-occipital ependymoma. Indian Journal of Pathology & Microbiology. 2025 Jun; 68(2): 431-434en_US
dc.identifier.issn0377-4929
dc.identifier.issn0974-5130
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/253961
dc.languageenen_US
dc.publisherWolters Kluwer - Medknowen_US
dc.relation.issuenumber2en_US
dc.relation.volume68en_US
dc.source.urihttps://doi.org/10.4103/ijpm.ijpm_323_23en_US
dc.subjectEpendymomaen_US
dc.subjectgliomaen_US
dc.subjectgliosarcomaen_US
dc.subjectimmunohistochemistryen_US
dc.subjectpendymosarcomaen_US
dc.titleEpendymosarcoma presenting as recurrence in a primary left parieto-occipital ependymomaen_US
dc.typeJournal Articleen_US
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