Combined hepatocellular and cholangiocarcinoma: CT findings with emphasis on multiphasic helical CT.

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dc.contributor.authorPhongkitkarun, Sithen_US
dc.contributor.authorSrisuwan, Tanopen_US
dc.contributor.authorSornmayura, Pattanaen_US
dc.contributor.authorJatchavala, Janjiraen_US
dc.date.accessioned2009-05-27T18:34:57Z
dc.date.available2009-05-27T18:34:57Z
dc.date.issued2007-01-12en_US
dc.descriptionChotmaihet Thangphaet.en_US
dc.description.abstractOBJECTIVE: To describe CT findings of patients with combined hepatocellular carcinoma and cholangiocarcinoma (HCC-CC) in correlation with clinical data and histopathological results. MATERIAL AND METHOD: Ten from 31 cases whose CT study was available were reviewed retrospectively in the aspect of imaging findings, clinical data, and pathological results. RESULTS: Most of the tumors were hypodense solitary mass with gradually enhanced after contrast administration. Bile duct dilatation was observed in two cases. The overall CT findings were more similar to CC rather than HCC despite the pathological result showing predominant HCC component. Serum alpha-fetoprotein level was normal or mildly elevated while an elevated concentration of carbohydrate antigen 19-9 was observed. Hepatitis profiles showed positive to hepatitis B virus infection in four cases and hepatitis C virus infection in one case. CONCLUSION: The diagnosis of combined HCC-CC should be considered if the tumor has similar findings to CC without bile duct dilatation on cirrhotic liver and the patient has normal or low rising of the AFP level with or without elevated CA 19-9 level. In non-cirrhotic liver, the finding is non-specific.en_US
dc.description.affiliationDepartment of Radiology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Rama VI Rd, Rajchathewi, Bangkok 10400, Thailand. rasih@ma.hidol.ac.then_US
dc.identifier.citationPhongkitkarun S, Srisuwan T, Sornmayura P, Jatchavala J. Combined hepatocellular and cholangiocarcinoma: CT findings with emphasis on multiphasic helical CT. Journal of the Medical Association of Thailand. 2007 Jan; 90(1): 113-20en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/39437
dc.language.isoengen_US
dc.source.urihttps://www.mat.or.th/journal/all.phpen_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshBile Duct Neoplasms --radiographyen_US
dc.subject.meshBile Ducts, Intrahepaticen_US
dc.subject.meshCA-19-9 Antigen --blooden_US
dc.subject.meshCarcinoma, Hepatocellular --radiographyen_US
dc.subject.meshCholangiocarcinoma --radiographyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshLiver Neoplasms --radiographyen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshNeoplasms, Multiple Primary --radiographyen_US
dc.subject.meshRadiographic Image Enhancementen_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshTomography, Spiral Computeden_US
dc.subject.meshalpha-Fetoproteins --analysisen_US
dc.titleCombined hepatocellular and cholangiocarcinoma: CT findings with emphasis on multiphasic helical CT.en_US
dc.typeJournal Articleen_US
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