Tumor necrosis factor alpha and interleukin 6 in infants with sepsis.

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dc.contributor.authorMakhija, Praveenen_US
dc.contributor.authorYadav, Sangitaen_US
dc.contributor.authorThakur, Archanaen_US
dc.date.accessioned2005-10-05en_US
dc.date.accessioned2009-05-27T04:54:16Z
dc.date.available2005-10-05en_US
dc.date.available2009-05-27T04:54:16Z
dc.date.issued2005-10-05en_US
dc.description.abstractThirty-two infants above one month of age admitted to a tertiary care hospital with signs of infection and presumptive diagnosis of sepsis were included. Cytokine levels of tumor necrosis factor alpha (TNFmu) and interleukin-6 (IL 6) were estimated at admission and after 48 to 72 hr, and their relationship examined to the outcome. Significantly higher TNFalpha and IL-6 levels were seen in infants with sepsis compared to control. The TNFalpha levels significantly decreased in patients with sepsis, septic shock and the survivors, while the patients who did not survive, the levels showed no significant change after 48 hr. The initial levels of IL6 were comparatively higher in patients with septic shock and non-survivors, and increased at 48 hr of admission in patients with sepsis, septic shock and non-survivors.en_US
dc.description.affiliationDepartment of Pediatrics, Maulana Azad Medical College and Associated Lok Nayak Hospital, New Delhi 110 002, India.en_US
dc.identifier.citationMakhija P, Yadav S, Thakur A. Tumor necrosis factor alpha and interleukin 6 in infants with sepsis. Indian Pediatrics. 2005 Oct; 42(10): 1024-8en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/6209
dc.language.isoengen_US
dc.source.urihttps://indianpediatrics.neten_US
dc.subject.meshBiological Markersen_US
dc.subject.meshCase-Control Studiesen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshIndia --epidemiologyen_US
dc.subject.meshInfanten_US
dc.subject.meshInterleukin-6 --blooden_US
dc.subject.meshMaleen_US
dc.subject.meshPrognosisen_US
dc.subject.meshProspective Studiesen_US
dc.subject.meshSepsis --blooden_US
dc.subject.meshShock, Septic --blooden_US
dc.subject.meshStatistics, Nonparametricen_US
dc.subject.meshTumor Necrosis Factor-alpha --metabolismen_US
dc.titleTumor necrosis factor alpha and interleukin 6 in infants with sepsis.en_US
dc.typeJournal Articleen_US
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