Study on Uric Acid as Biomarker for Insulin Resistance in Type 2 Diabetic Mellitus

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dc.contributor.authorVerma, Prabhaen_US
dc.contributor.authorVerma, Sadhanaen_US
dc.contributor.authorJaiswal, Sapnaen_US
dc.contributor.authorAnand, Bhupinder Kauren_US
dc.contributor.authorMarwaha, MPSen_US
dc.date.accessioned2020-01-02T06:07:34Z
dc.date.available2020-01-02T06:07:34Z
dc.date.issued2019-03
dc.description.abstractSerum uric acid (SUA) is an end product of purine metabolism. SUA is excreted mainly through the kidneys. Multiple mechanisms have been reported to show the association of hyperuricemia with glucose intolerance. The association between insulin and renal resistance to absorption of urates has been found out to be the most important among these mechanisms. Methods: This comparative study contains 50 subjects of type 2 diabetes having an age group of 40-65 years were participated in case & 50 healthy subjects as control group. This case control study conducted in the department of department of biochemistry, LPS institute of Cardiology, GSVM medical college, Kanpur. Results: In the case-control study were found 54% male and 46% female in case group & 42% female and 58% female. We suggested that in study group 44% cases were belongs to 61-65 age group followed by other while in control group 42% were belongs to 61-65 age group followed by other age group. Conclusion: This study conclude that there were significant correlation between uric acid and HOMA-IR value. Hyperuricemia is related to risk factors for insulin resistance in type 2 diabetes. The study concluded a significant progressive relationship between increased uric acid level with respect to HOMA-IR levels which is an indices of insulin resistance.en_US
dc.identifier.affiliationsAssistant Professor, Department of Biochemistry, M.L.B. Medical College, Jhansi.en_US
dc.identifier.affiliationsAssistant Professor, Department of Biochemistry, LPS Institute of Cardiology, Gsvm Medical College, Kanpur.en_US
dc.identifier.affiliationsTutor, Department of Biochemistry, Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow.en_US
dc.identifier.affiliationsProfessor, Department of Community Medicine, SGT Medical College, Gurugram.en_US
dc.identifier.affiliationsClassified Specialist Aviation Medicine, Air Force Centre Medical Establishment, New Delhi.en_US
dc.identifier.citationVerma Prabha, Verma Sadhana, Jaiswal Sapna, Anand Bhupinder Kaur, Marwaha MPS. Comparative Study on Serum Calcium Level in Preeclampsia Patients and Normal Pregnancy at Medical College & Hospital. Annals of International medical and Dental Research. 2019 Mar; 5(2): 9-12en_US
dc.identifier.issn2395-2822
dc.identifier.issn2395-2814
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/188736
dc.languageenen_US
dc.publisherSociety for Health Care & Research Developmenten_US
dc.relation.issuenumber2en_US
dc.relation.volume5en_US
dc.source.urihttps://doi.org/10.21276/aimdr.2019.5.2.BC3en_US
dc.subjectSerum uric aciden_US
dc.subjectType 2 diabetes mellitusen_US
dc.subjectHOMA-IRen_US
dc.titleStudy on Uric Acid as Biomarker for Insulin Resistance in Type 2 Diabetic Mellitusen_US
dc.typeJournal Articleen_US
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