Influence of calcium removal from bath solution on isolated rat duodenum contractions.

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dc.contributor.authorSüer, Cen_US
dc.contributor.authorErenmemisoglu, Aen_US
dc.contributor.authorTemocin, Sen_US
dc.contributor.authorAkar, Sen_US
dc.contributor.authorBeydagi, Hen_US
dc.contributor.authorTaspolat, Ien_US
dc.date.accessioned1992-07-01en_US
dc.date.accessioned2009-06-01T08:32:44Z
dc.date.available1992-07-01en_US
dc.date.available2009-06-01T08:32:44Z
dc.date.issued1992-07-01en_US
dc.description.abstractIn this study whether extracellular Ca++ is essential to produce an increase of tension of isolated rat duodenum by ACh, 5-HT, AVP and KCl-, was examined. KCl- and AVP-evoked contractions were almost totally prevented by Ca++ removal from bath solution. The increase of tension of isolated duodenum caused by ACh or 5-HT was totally prevented after adding nifedipine, a Ca++ channel blocker, into Ca free solution. Our results suggest that ACh or 5-HT utilizes intracellular as well as extracellular sources of Ca++ to produce contraction in rat duodenum, whereas AVP-or KCl evoked contraction was mainly due to influx of Ca from extracellular sources.en_US
dc.description.affiliationDepartment of Physiology, Erciyes University, Medical Faculty, Kayser, Turkey.en_US
dc.identifier.citationSüer C, Erenmemisoglu A, Temocin S, Akar S, Beydagi H, Taspolat I. Influence of calcium removal from bath solution on isolated rat duodenum contractions. Indian Journal of Physiology and Pharmacology. 1992 Jul; 36(3): 181-4en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/108988
dc.language.isoengen_US
dc.source.urihttps://www.ijpp.comen_US
dc.subject.meshAcetylcholine --pharmacologyen_US
dc.subject.meshAnimalsen_US
dc.subject.meshArginine Vasopressin --pharmacologyen_US
dc.subject.meshCalcium --pharmacologyen_US
dc.subject.meshDuodenum --drug effectsen_US
dc.subject.meshMuscle Contraction --drug effectsen_US
dc.subject.meshMuscle, Smooth --drug effectsen_US
dc.subject.meshNifedipine --pharmacologyen_US
dc.subject.meshPotassium Chloride --pharmacologyen_US
dc.subject.meshRatsen_US
dc.subject.meshSerotonin --pharmacologyen_US
dc.titleInfluence of calcium removal from bath solution on isolated rat duodenum contractions.en_US
dc.typeIn Vitroen_US
dc.typeJournal Articleen_US
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