Cancer stem cell: A rogue responsible for tumor development and metastasis.

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dc.contributor.authorKapoor, Aditi
dc.contributor.authorKumar, Sudhir
dc.date.accessioned2014-12-31T07:39:51Z
dc.date.available2014-12-31T07:39:51Z
dc.date.issued2014-07
dc.description.abstractCancer stem cells are a small population of cells in a tumor. They have the ability to self-renew and maintain the tumor. The most apt and accepted hypothesis for tumor development is Cancer Stem Cells. This review focuses on this concept of cancer stem cells, serving their purpose and leading to the development of tumor. There are many cell biomarkers which have been described for the identification and characterization of cancer stem cells. The most prominent of the cellular markers for the detection of cancer stem cells; CD133, CD44, ALDH-1 along with some others have been discussed in detail in this review.en_US
dc.identifier.citationKapoor Aditi, Kumar Sudhir. Cancer stem cell: A rogue responsible for tumor development and metastasis. Indian Journal of Cancer. 2014 Jul-Sep; 51(3): 282-289.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/154383
dc.language.isoenen_US
dc.source.urihttps://www.indianjcancer.com/article.asp?issn=0019-509X;year=2014;volume=51;issue=3;spage=282;epage=289;aulast=Kapooren_US
dc.subjectClonal evolutionen_US
dc.subjectmulti-potencyen_US
dc.subjectoncogenesen_US
dc.subjectpre-cancerous stem cellsen_US
dc.subjectself-renewalen_US
dc.subjecttumor suppressor genesen_US
dc.subject.meshGenes, Tumor Suppressor --genetics
dc.subject.meshNeoplasm Metastasis --etiology
dc.subject.meshNeoplasms --growth & development
dc.subject.meshNeoplastic Stem Cells --growth & development
dc.subject.meshOncogenes --genetics
dc.subject.meshPrecancerous Conditions --etiology
dc.titleCancer stem cell: A rogue responsible for tumor development and metastasis.en_US
dc.typeArticleen_US
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