Evaluation of an automated erythrocyte sedimentation rate analyzer as compared to the Westergren manual method in measurement of erythrocyte sedimentation rate.

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dc.contributor.authorSubramanian, Arulselvi
dc.contributor.authorRangarajan, Kanchana
dc.contributor.authorPandey, Ravindra Mohan
dc.contributor.authorGandhi, Jatin S
dc.contributor.authorSharma, Vijay
dc.contributor.authorBhoi, Sanjeev Kumar
dc.date.accessioned2012-10-04T06:02:33Z
dc.date.available2012-10-04T06:02:33Z
dc.date.issued2011-01
dc.description.abstractContext: Monitor 100® (Electa Lab, Italy) is a newly developed automated method for measurement of erythrocyte sedimentation rate (ESR). Aims: The aim of our study was to compare the ESR values by Monitor 100® against the standard Westergren method. Patients and Methods: This cross-sectional study was conducted at a Level I trauma care center on 200 patients. The samples taken were as per the recommendations charted out by International Council for Standardization in Hematology (ICSH) for comparing automated and manual Westergrens method. Statistical Analysis Used: Bland and Altman statistical analysis was applied for evaluating Monitor 100® against the conventional Westergren method. Results: The analysis revealed a low degree of agreement between the manual and automated methods especially for higher ESR values, mean difference -11.2 (95% limits of agreement, -46.3 to 23.9) and mean difference -13.4 (95% limits of agreement-58.9 to 32.1) for 1 and 2 hours, respectively. This discrepancy which is of clinical significance was less evident for ESR values in the normal range <25 mm/hour (-7.7 mean of difference; -18.9 to 3.5 limits of agreement). Conclusions: The fully automated system Monitor 100® for ESR measurement tends to underestimate the manual ESR readings. Hence it is recommended that a correction factor be applied for the range of ESR values while using this equipment. Further studies and validation experiments would be required.en_US
dc.identifier.citationSubramanian Arulselvi, Rangarajan Kanchana, Pandey Ravindra Mohan, Gandhi Jatin S, Sharma Vijay, Bhoi Sanjeev Kumar. Evaluation of an automated erythrocyte sedimentation rate analyzer as compared to the Westergren manual method in measurement of erythrocyte sedimentation rate. Indian Journal of Pathology & Microbiology. 2011 Jan-Mar 54(1): 70-74.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/141919
dc.language.isoenen_US
dc.source.urihttps://www.ijpmonline.org/article.asp?issn=0377-4929;year=2011;volume=54;issue=1;spage=70;epage=74;aulast=Subramanianen_US
dc.subjectComparisonen_US
dc.subjecterythrocyte sedimentation rateen_US
dc.subjectMonitor 100®en_US
dc.subjectWestergren methoden_US
dc.subject.meshAdolescent
dc.subject.meshAdult
dc.subject.meshAged
dc.subject.meshAged, 80 and over
dc.subject.meshAutomation --methods
dc.subject.meshBlood Sedimentation
dc.subject.meshChild
dc.subject.meshChild, Preschool
dc.subject.meshClinical Laboratory Techniques --methods
dc.subject.meshCross-Sectional Studies
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshInfant
dc.subject.meshInfant, Newborn
dc.subject.meshInflammation --diagnosis
dc.subject.meshItaly
dc.subject.meshMale
dc.subject.meshMiddle Aged
dc.subject.meshYoung Adult
dc.titleEvaluation of an automated erythrocyte sedimentation rate analyzer as compared to the Westergren manual method in measurement of erythrocyte sedimentation rate.en_US
dc.typeArticleen_US
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