A Prospective Observational Study of Spectrum of Tropical Infections in Pregnancy in a Tertiary Care Hospital in Mumbai, Maharashtra

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dc.contributor.authorSharma, Gauraven_US
dc.contributor.authorRedkar, Neelam Nen_US
dc.contributor.authorRelwani, Prakashen_US
dc.contributor.authorYadav, Sameer Sen_US
dc.contributor.authorPandey, Sheelaen_US
dc.date.accessioned2023-08-09T06:13:38Z
dc.date.available2023-08-09T06:13:38Z
dc.date.issued2022-06
dc.description.abstractBackground and aims: Pregnancy is associated with several hormonal and mechanical changes in the body. The tropical infections that most commonly affect pregnant females are malaria, dengue, leptospirosis and typhoid. These tropical infections cause many medical complications in pregnancy by causing anemia, thrombocytopenia, bleeding and inflammatory reactions. Therefore, we conducted a study to evaluate the clinical presentation, complications and outcome of tropical infections in pregnancy. Material and methods: The present study was conducted at a tertiary care hospital in Mumbai, Maharashtra over a period of 1½ year (January 2018 to June 2019) after getting approval from Institutional Ethics Committee. In this study, 250 pregnant patients admitted in medicine ward, obstetrics and gynecology ward, and ICU with symptoms and signs of tropical infections and age more than 18 years, who gave written informed consent, were included. Results: The most common age group amongst the study population was 20 to 24 years (41.6%), followed by 25 to 29 years (40%) and 30 to 35 years (18.4%). Most of the study population had gestational age of 1 to 12 weeks (61.6%), followed by 13 to 28 weeks (31.6%) and more than 28 weeks (6.8%). Most of the study population had parity 2 (46.8%), followed by parity 1 (43.2%), parity 3 (6.8%) and parity 4 (3.2%). The most common clinical features amongst the study population was fever (62%), followed by headache (32.8%), nausea (30.8%), pain in abdomen (26.4%) and petechiae (26%). The most common infections amongst the study population were malaria (11.2%), dengue (8%), leptospirosis (6%) and enteric fever (5.2%). The most common medical complications were bleeding due to thrombocytopenia (TCP) (6.8%), followed by serositis (5.2%), ARDS (4.4%), meningitis (2.8%), subconjunctival hemorrhage (2.8%) and encephalitis (1.4%). Complicated infections were seen in 30% of the study population. Conclusion: All pregnant women must be evaluated at primary care centers properly in their antenatal visits for their parity status and any associated risk factors and diseases. By doing this, we can reduce many tropical infections, complications and maternal mortality in early stage of pregnancy.en_US
dc.identifier.affiliationsJunior Resident (3rd Year)en_US
dc.identifier.affiliationsProfessor and HODen_US
dc.identifier.affiliationsAssistant Professoren_US
dc.identifier.affiliationsAssociate Professor Dept. of General Medicine, HBT Medical College, Mumbai, Maharashtraen_US
dc.identifier.citationSharma Gaurav, Redkar Neelam N, Relwani Prakash, Yadav Sameer S, Pandey Sheela. A Prospective Observational Study of Spectrum of Tropical Infections in Pregnancy in a Tertiary Care Hospital in Mumbai, Maharashtra. Indian Journal of Clinical Practice. 2022 Jun; 33(1): 17-21en_US
dc.identifier.issn0971-0876
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/222062
dc.languageenen_US
dc.publisherIJCP Groupen_US
dc.relation.issuenumber1en_US
dc.relation.volume33en_US
dc.source.urihttps://ijcp.in/Pages/Post_Detail.aspx?wid=20385&A%20Prospective%20Observational%20Study%20of%20Spectrum%20of%20Tropical%20Infections%20in%20Pregnancy%20in%20a%20Tertiary%20Care%20Hospital%20in%20Mumbai,%20Maharashtraen_US
dc.subjectPregnancyen_US
dc.subjecttropical infectionsen_US
dc.subjectmalariaen_US
dc.subjectdengueen_US
dc.subjectleptospirosisen_US
dc.subjectthrombocytopeniaen_US
dc.titleA Prospective Observational Study of Spectrum of Tropical Infections in Pregnancy in a Tertiary Care Hospital in Mumbai, Maharashtraen_US
dc.typeJournal Articleen_US
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