A comparative evaluation of pilocarpine 1% and clonidine 0.125% versus timolol 0.5%.

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dc.contributor.authorSihota, Ren_US
dc.contributor.authorAgarwal, H Cen_US
dc.contributor.authorRajashekar, Y Len_US
dc.date.accessioned1996-06-01en_US
dc.date.accessioned2009-05-29T07:51:56Z
dc.date.available1996-06-01en_US
dc.date.available2009-05-29T07:51:56Z
dc.date.issued1996-06-01en_US
dc.description.abstractAll the presently available antiglaucoma medications have either local or systemic adverse effects. Combinations of drugs are being used not only to increase the effectivity and compliance but also to decrease the incidence and magnitude of side effects. The single dose response of open angle glaucoma eyes to pilocarpine 1%, clonidine 0.125%, a combination of pilocarpine 1% and clonidine 0.125%, and timolol 0.5% was studied in a double blind, masked, cross over study. Over a period of twelve hours the effectivity of the combination of pilocarpine 1% and clonidine 0.125% was significantly more than that of either drug alone and was found to be similar to that of timolol 0.5%. No local or systemic adverse effects were seen.en_US
dc.description.affiliationDr. Rajendra Prasad Centre for Ophthalmic Sciences, A.I.I.M.S. New Dehi.en_US
dc.identifier.citationSihota R, Agarwal HC, Rajashekar YL. A comparative evaluation of pilocarpine 1% and clonidine 0.125% versus timolol 0.5%. Indian Journal of Ophthalmology. 1996 Jun; 44(2): 87-9en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/69828
dc.language.isoengen_US
dc.source.urihttps://www.ijo.inen_US
dc.subject.meshAdministration, Topicalen_US
dc.subject.meshAdrenergic alpha-Agonists --administration & dosageen_US
dc.subject.meshAdrenergic beta-Antagonists --administration & dosageen_US
dc.subject.meshAdulten_US
dc.subject.meshBlood Pressure --drug effectsen_US
dc.subject.meshClonidine --administration & dosageen_US
dc.subject.meshCross-Over Studiesen_US
dc.subject.meshDouble-Blind Methoden_US
dc.subject.meshDrug Therapy, Combinationen_US
dc.subject.meshFemaleen_US
dc.subject.meshGlaucoma, Open-Angle --drug therapyen_US
dc.subject.meshHumansen_US
dc.subject.meshIntraocular Pressure --drug effectsen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshMuscarinic Agonists --administration & dosageen_US
dc.subject.meshOphthalmic Solutionsen_US
dc.subject.meshPilocarpine --administration & dosageen_US
dc.subject.meshTimolol --administration & dosageen_US
dc.titleA comparative evaluation of pilocarpine 1% and clonidine 0.125% versus timolol 0.5%.en_US
dc.typeClinical Trialen_US
dc.typeJournal Articleen_US
dc.typeRandomized Controlled Trialen_US
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