Spontaneous bacterial peritonitis (SBP) in cirrhotic ascites: a prospective study in a tertiary care hospital, Nepal.

Simple item page
dc.contributor.authorSyed, V Aen_US
dc.contributor.authorAnsari, J Aen_US
dc.contributor.authorKarki, Pen_US
dc.contributor.authorRegmi, Men_US
dc.contributor.authorKhanal, Ben_US
dc.date.accessioned2009-05-28T03:55:06Z
dc.date.available2009-05-28T03:55:06Z
dc.date.issued2007-01-08en_US
dc.descriptionKathmandu University Medical Journal.en_US
dc.description.abstractBACKGROUND: Spontaneous bacterial peritonitis (SBP) is one of the potentially lethal complications of cirrhosis and is defined as infected ascites in the absence of any recognizable secondary cause of infection. Objective was to study the occurrence of SBP, clinical and laboratory characteristics and the response to antibiotics. METHODS: We had prospectively evaluated 81 cirrhotic patients with ascites during one-year period. All SBP patients were treated with cefotaxime, 2gm IV, every 12h for 5days. RESULTS: Of these 81 patients, 24.67% of patients (n=20) had SBP and its variants (classical SBP n= 4, CNNA n=13 and bacterascites n=3). There were thirteen males and 7 females in the study.85% of the cases had Child;s class C cirrhosis. UGI bleeding and abdominal pain were the most common presenting symptoms of SBP. Culture positives were 35% (n=7). The most frequent organisms were Escherichia coli (n=3) and Streptococcus pneumoniae (n=2). 94% of the patients responded to therapy after 48 hours of treatment. Total resolution after 5 days of therapy was 73% and in-hospital mortality was 15% (n=3). CONCLUSION: SBP, if diagnosed early can be treated with very good success rate up to 73%. Appropriate treatment of SBP with cefotaxime can help in reducing mortality and morbidity in patients with chronic liver disease.en_US
dc.description.affiliationDepartment Of Internal Medicine BP Koirala Institute Of Health Sciences, Dharan, Nepal. vaqarahmad@yahoo.comen_US
dc.identifier.citationSyed VA, Ansari JA, Karki P, Regmi M, Khanal B. Spontaneous bacterial peritonitis (SBP) in cirrhotic ascites: a prospective study in a tertiary care hospital, Nepal. Kathmandu University Medical Journal. 2007 Jan-Mar; 5(1): 48-59en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/46109
dc.language.isoengen_US
dc.source.urihttps://www.kumj.com.npen_US
dc.source.urihttps://kumj.com.np/ftp/issue/17/48-59-Spontaneous-bacterial-peritonitis.pdfen_US
dc.subject.meshAnti-Bacterial Agents --therapeutic useen_US
dc.subject.meshAscites --complicationsen_US
dc.subject.meshBacterial Infections --drug therapyen_US
dc.subject.meshCefotaxime --therapeutic useen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshLiver Cirrhosis --complicationsen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshNepal --epidemiologyen_US
dc.subject.meshPeritonitis --drug therapyen_US
dc.subject.meshProspective Studiesen_US
dc.subject.meshTreatment Outcomeen_US
dc.titleSpontaneous bacterial peritonitis (SBP) in cirrhotic ascites: a prospective study in a tertiary care hospital, Nepal.en_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
kumj2007v5n1p.48.pdf
Size:
145.6 KB
Format:
Adobe Portable Document Format
Description:
Journal article
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description:
Download
Collections
Kathmandu University Medical Journal