ANTIPROLIFERATIVE EFFECT ON COLON CANCER CELL LINES BY AQUEOUS EXTRACT FROM THE BARK OF MILLINGTONIA HORTENSIS

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dc.contributor.authorSiwapong Tansuwanwongen_US
dc.contributor.authorHiroyuki Yamamotoen_US
dc.contributor.authorKohzoh Imaien_US
dc.contributor.authorUsanee Vinitketkumnuenen_US
dc.date.accessioned2011-02-16T09:16:40Z
dc.date.available2011-02-16T09:16:40Z
dc.date.created2007-11-30en_US
dc.date.issued2007-11-30en_US
dc.description.abstractMillingtonia hortensis is a traditional medicinal plant widely used in South-East Asia. This study focused on the antiproliferative effect when comparing between aqueous extract and ethanol extract from the bark of M. hortensis using human colon cancer cell lines, DLD-1, HCT15, SW48 and SW480. In in vitro experiments, the MTT method was used to determine the antiproliferative effect of M. hortensis extract on colon cancer cells. An aqueous extract of M. hortensis significantly reduced the proliferation rate of colon cancer cell lines in a dose-dependent manner. However, no antiproliferative effect was observed by ethanol extract of M. hortensis. This finding indicated that only aqueous extract from the bark of M. hortensis is able to inhibit colon cancer cell proliferation, and its mechanism is now under investigation.en_US
dc.identifier.citationChiang Mai Medical Journal; Vol.46 No.2 June 2007 (pages 45 - 91); 61 - 66en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/130652
dc.language.isoen_USen_US
dc.publisherChiang Mai Medical Journalen_US
dc.rightsChiang Mai Medical Journalen_US
dc.source.urihttps://thailand.digitaljournals.org/index.php/CMMJ/issue/archiveen_US
dc.source.urihttps://thailand.digitaljournals.org/index.php/CMMJ/article/view/52en_US
dc.titleANTIPROLIFERATIVE EFFECT ON COLON CANCER CELL LINES BY AQUEOUS EXTRACT FROM THE BARK OF MILLINGTONIA HORTENSISen_US
dc.typeOriginal Articlesen_US
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