Navigating Choices: A Questionnaire-based Study on Usage of Antiplatelet Therapies in Management of Acute Coronary Syndrome in India
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Date
2024-05
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Publisher
IJCP Group
Abstract
Background: Percutaneous coronary intervention (PCI) is a common invasive cardiac procedure used to treat acute coronary syndrome (ACS). The main objective of anticoagulant therapy in PCI is to minimize the risk of plaque rupture and decrease the formation of blood clots. Understanding clinicians' prescription patterns is crucial for optimizing treatment strategies for patients with ACS who have undergone PCI. Methods: It was a cross-sectional, questionnaire-based, noninterventional study which included questionnaire responses from 136 cardiologists, regarding usage of antiplatelets in ACS management. Results: Ticagrelor and aspirin dual antiplatelet therapy (DAPT) is favored by 54% cardiologists in managing ACS patients who have undergone PCI, regardless of the presence or absence of type 2 diabetes mellitus (T2DM). Further, 78% of the participants preferred long-term DAPT over short-term and medium-term alternatives. Forty percent respondents preferred a 1-month triple antithrombotic therapy (TAT) for PCI patients with atrial fibrillation. Additionally, the study emphasized the importance of considering factors like age, bleeding history, hemoglobin, and creatinine clearance in determining the optimal antithrombotic strategy. Conclusion: This study contributes valuable insights into the real-world practices of health care practitioners, paving the way for more informed and personalized ACS management strategies in Indian patients.
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Keywords
Percutaneous coronary intervention, acute coronary syndrome, dual antiplatelet therapy, ticagrelor
Citation
Kerkar Prafulla, Prajapati Jayesh, Sahoo PK, Rastogi Pankaj, Banerjee Sunip, Ray Saumitra, Desai Bhupen, Sathe Sunil, Christopher Johann, Murthy Narayana, Shah Chetan, Mayabhate Mayur, Dali Jessica . Navigating Choices: A Questionnaire-based Study on Usage of Antiplatelet Therapies in Management of Acute Coronary Syndrome in India. Indian Journal of Clinical Practice. 2024 May; 34(12): 14-20