Ligand binding prediction for BRCA1, a key molecule in the pathogensis of breast cancer.

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dc.contributor.authorWiwanitkit, V
dc.date.accessioned2013-01-15T04:59:02Z
dc.date.available2013-01-15T04:59:02Z
dc.date.issued2010-04
dc.description.abstractBackground : Cell adhesion plays a pivotal role in diverse biological processes that occur in oncogenesis. BRCA1 was the first breast cancer susceptibility gene to be successfully identified and cloned. The role of BRCA1 as a predictive marker of chemotherapy response in breast cancer is proposed. Ligand binding is an important factor in the success of chemoprevention. Materials and Methods : In this work, the author performed a ligand-binding prediction for BRCA1 using a new bioinformatics tool. Results : According to this study, 10 strong possible ligands were identified. Conclusion : These sites can be useful for further drug development studies.en_US
dc.identifier.citationWiwanitkit V. Ligand binding prediction for BRCA1, a key molecule in the pathogensis of breast cancer. Indian Journal of Cancer. 2010 Apr-June; 47(2): 139-141.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/144318
dc.language.isoenen_US
dc.source.urihttps://www.indianjcancer.com/article.asp?issn=0019-509X;year=2010;volume=47;issue=2;spage=139;epage=141;aulast=Wiwanitkiten_US
dc.subjectBRCA1en_US
dc.subjectligand bindingen_US
dc.subject.meshBRCA1 Protein --metabolism
dc.subject.meshBreast Neoplasms --diagnosis
dc.subject.meshBreast Neoplasms --metabolism
dc.subject.meshComputational Biology
dc.subject.meshDrug Design
dc.subject.meshFemale
dc.subject.meshGene Expression Regulation, Neoplastic
dc.subject.meshHumans
dc.subject.meshPrognosis
dc.subject.meshTumor Markers, Biological --metabolism
dc.titleLigand binding prediction for BRCA1, a key molecule in the pathogensis of breast cancer.en_US
dc.typeArticleen_US
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