An outbreak of dengue fever in periurban slums of Chandigarh, India, with special reference to entomological and climatic factors.

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dc.contributor.authorRatho, R Ken_US
dc.contributor.authorMishra, Ben_US
dc.contributor.authorKaur, Jen_US
dc.contributor.authorKakkar, Nen_US
dc.contributor.authorSharma, Ken_US
dc.date.accessioned2005-12-31en_US
dc.date.accessioned2009-05-29T06:59:25Z
dc.date.available2005-12-31en_US
dc.date.available2009-05-29T06:59:25Z
dc.date.issued2005-12-31en_US
dc.description.abstractBACKGROUNDS: Dengue viral infection is one of the most important public health problem in tropical countries. AIM: An outbreak of dengue fever was investigated in a periurban slum area of Chandigarh, India, during September to December, 2002. MATERIALS AND METHODS: Blood samples from 218 patients and 30 apparently healthy contacts were tested for dengue-specific immunoglobulin M (IgM) and IgG antibodies including 80 acute samples collected within 5 days of illness were subjected for virus isolation in newborn mice. The average temperature, rainfall, and humidity of the epidemic year were compared with the number of dengue cases. STATISTICAL ANALYSIS: statistical significance was found out using c2-test. RESULTS: A total of 76 cases were positive by either dengue IgM capture assay (n = 57) or virus isolation (n = 17) or both (n = 2). Fifteen of nineteen viral isolates subjected for typing by type-specific multiplex reverse transcription-polymerase chain reaction were found to be of dengue virus. High rainfall and humidity with the temperature range from 21 degrees C to 33 degrees C during the months of August and September might have favored the breeding of mosquitoes, thus leading to an increase in the number of dengue cases in October and November, 2002. CONCLUSION: The present outbreak thus emphasizes the need for continuous sero epidemiological and entomological surveillance for the timely implementation of effective dengue control programme.en_US
dc.description.affiliationDepartment of Virology, Post Graduate Institute of Medical Education & Research, General Hospital, Sector-16, Chandigarh., India. rathopgi@yahoo.comen_US
dc.identifier.citationRatho RK, Mishra B, Kaur J, Kakkar N, Sharma K. An outbreak of dengue fever in periurban slums of Chandigarh, India, with special reference to entomological and climatic factors. Indian Journal of Medical Sciences. 2005 Dec; 59(12): 518-26en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/69442
dc.language.isoengen_US
dc.source.urihttps://www.indianjmedsci.orgen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAedesen_US
dc.subject.meshAnimalsen_US
dc.subject.meshAntibodies, Viral --blooden_US
dc.subject.meshChi-Square Distributionen_US
dc.subject.meshChilden_US
dc.subject.meshClimateen_US
dc.subject.meshDengue --epidemiologyen_US
dc.subject.meshDisease Outbreaksen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshIndia --epidemiologyen_US
dc.subject.meshMaleen_US
dc.subject.meshMiceen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPoverty Areasen_US
dc.subject.meshReverse Transcriptase Polymerase Chain Reactionen_US
dc.subject.meshSerologic Testsen_US
dc.subject.meshUrban Populationen_US
dc.titleAn outbreak of dengue fever in periurban slums of Chandigarh, India, with special reference to entomological and climatic factors.en_US
dc.typeJournal Articleen_US
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