Comparative Evaluation of Ropivacaine Alone with Ropivacaine Nalbuphine Combination in Supraclavicular Brachial Plexus Block for Upper Limb Surgery

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dc.contributor.authorJadeja, Pritien_US
dc.contributor.authorGohel, Jahnavi Aen_US
dc.date.accessioned2020-10-16T08:37:59Z
dc.date.available2020-10-16T08:37:59Z
dc.date.issued2019-11
dc.description.abstractBackground and Aims: The benefit of post-operative analgesia in regional block is short lived due to limited duration of theaction of local anesthetics. Various adjuvants have been tried to enhance the duration of analgesia. The aim of this study wasto evaluate the analgesic efficacy and safety of nalbuphine as an adjuvant to 0.5% ropivacaine for supraclavicular brachialplexus block.Materials and Methods: A prospective, randomized, double-blind study was conducted on 60 patients of American Societyof Anesthesiologists physical Status I/II aged 18–60 years scheduled for upper limb surgeries under supraclavicular brachialplexus block. The patients were randomly allocated into two groups of 30 each to receive either 30 ml of 0.5% ropivacainewith 1 ml of normal saline (Group R) or 30 ml of 0.5% ropivacaine with 1 ml (10 mg) of nalbuphine (Group RN). The onset andduration of sensory and motor block, duration of analgesia, and side effects were noted.Results: The mean onset time for a complete sensory and motor block in Group RN was shorter (8.37 ± 0.79 min; 17.67 ± 1.07 min)as compare to Group R (10.9 ± 1.11 min; 19.17 ± 0.86 min). The mean duration of sensory and motor block in Group RN waslonger (725.67 ± 16.06 min; 420.33 ± 14.94 min) as compare to Group R (473.0 ± 22.67 min; 359.67 ± 26.89 min). The meanduration of analgesia in Group RN was 846.33 ± 72.50 min and in Group R was 588.0 ± 27.37 min. All results were statisticallysignificant (P < 0.0001). No significant side effects were observed in any of the two groups (P > 0.05).Conclusion: Nalbuphine as an adjuvant to ropivacaine in the supraclavicular brachial block significantly shortens the onsettime for sensory and motor block and prolongs the duration of sensory and motor blocks with longer duration of post-operativeanalgesia.en_US
dc.identifier.affiliationsAssociate Professor, Department of Anesthesia, Shri M. P. Shah Government Medical College, Guru Gobind Singh Hospital, Jamnagar, Gujarat, Indiaen_US
dc.identifier.affiliationsTutor, Department of Anesthesia, Shri M. P. Shah Government Medical College, Guru Gobind Singh Hospital, Jamnagar, Gujarat, Indiaen_US
dc.identifier.citationJadeja Priti, Gohel Jahnavi A. Comparative Evaluation of Ropivacaine Alone with Ropivacaine Nalbuphine Combination in Supraclavicular Brachial Plexus Block for Upper Limb Surgery. International Journal of Scientific Study. 2019 Nov; 7(8): 85-91en_US
dc.identifier.issn2321-595X
dc.identifier.issn2321-6354
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/209220
dc.languageenen_US
dc.publisherInternational Research Organization for Life & Health Sciences (IROLHS)en_US
dc.relation.issuenumber8en_US
dc.relation.volume7en_US
dc.source.urihttps://www.ijss-sn.com/uploads/2/0/1/5/20153321/16_ijss_nov_oa13_-_2019.pdfen_US
dc.subjectAnalgesiaen_US
dc.subjectNalbuphineen_US
dc.subjectRopivacaineen_US
dc.subjectSupraclavicular brachial plexusen_US
dc.titleComparative Evaluation of Ropivacaine Alone with Ropivacaine Nalbuphine Combination in Supraclavicular Brachial Plexus Block for Upper Limb Surgeryen_US
dc.typeJournal Articleen_US
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