Patch testing with expired Indian patch test kits: Results of a pilot study

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dc.contributor.authorMahajan, Vikram K.en_US
dc.contributor.authorChauhan, Pushpinder Singhen_US
dc.contributor.authorMehta, Karaninder Singhen_US
dc.contributor.authorSharma, Anujen_US
dc.contributor.authorChowdhary, Bhumikaen_US
dc.contributor.authorDhattarwal, Niharikaen_US
dc.contributor.authorSharma, Hitenderen_US
dc.contributor.authorChandel, Monikaen_US
dc.contributor.authorVerma, Yog Rajen_US
dc.date.accessioned2023-08-10T07:29:33Z
dc.date.available2023-08-10T07:29:33Z
dc.date.issued2022-04
dc.description.abstractBackground: The reliability of patch testing with expired Indian standard patch test kits has been not evaluated before. Methods: Thirty adults (men:women 25:5) with allergic contact dermatitis were divided into three groups of ten patients each for patch testing by Finn chamberĀ® method using Indian standard patch test kits having expiry in 2016, 2015 and 2014. The results were compared with those from a new kit with 2018 expiry. Results: Ten patients in group-1, eight patients in group-2 and seven patients in group-3 developed positive reactions of identical intensities and mostly from identical allergens from all four kits. The major contact allergens eliciting positive reactions of identical intensities were parthenium in nine, five and three patients, colophony in four, one and zero patients, fragrance mix in three, three and one patients, thiuram mix in three, one and one patients, and paraphenylene diamine in two, one and three patients from group-1,-2, and -3, respectively. Limitations: Small number of patients in each group remains the major limitation of the study. Whether or not these results can be extrapolated with patch test results from other similar patch test kits available across countries also needs confirmation. Conclusion: The patch test allergens can be used beyond labeled expiry dates but needs confirmation by a few large studies and using other available patch test kits. This is important as the relevance of patch test results for individual allergen in this scenario may remain debatable requiring careful interpretationen_US
dc.identifier.affiliationsDepartment of Dermatology, Venereology and Leprosy, Dr. Rajendra Prasad Government Medical College, Kangra (Tanda), Himachal Pradesh, Indiaen_US
dc.identifier.citationMahajan, Vikram K.en_US
dc.identifier.citationChauhan, Pushpinder Singhen_US
dc.identifier.citationMehta, Karaninder Singhen_US
dc.identifier.citationSharma, Anujen_US
dc.identifier.citationChowdhary, Bhumikaen_US
dc.identifier.citationDhattarwal, Niharikaen_US
dc.identifier.citationSharma, Hitenderen_US
dc.identifier.citationChandel, Monikaen_US
dc.identifier.citationVerma, Yog Raj. Patch testing with expired Indian patch test kits: Results of a pilot study. Indian Journal of Dermatology, Venereology and Leprology. 2022 Apr; 88(2): 188-195en_US
dc.identifier.issn0973-3922
dc.identifier.issn0378-6323
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/222921
dc.languageenen_US
dc.publisherScientific Scholaren_US
dc.relation.issuenumber2en_US
dc.relation.volume88en_US
dc.source.urihttps://doi.org/10.25259/IJDVL_390_19en_US
dc.subjectAirborne contact dermatitisen_US
dc.subjectallergic contact dermatitisen_US
dc.subjectIndian patch test seriesen_US
dc.subjectpartheniumen_US
dc.subjectPatch testen_US
dc.titlePatch testing with expired Indian patch test kits: Results of a pilot studyen_US
dc.typeJournal Articleen_US
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