A comparison of the clinical efficacy of ranitidine and sucralfate in reflux oesophagitis.

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dc.contributor.authorChopra, B Ken_US
dc.contributor.authorKazal, H Len_US
dc.contributor.authorMittal, P Ken_US
dc.contributor.authorSibia, S Sen_US
dc.date.accessioned1992-03-01en_US
dc.date.accessioned2009-05-31T04:43:18Z
dc.date.available1992-03-01en_US
dc.date.available2009-05-31T04:43:18Z
dc.date.issued1992-03-01en_US
dc.description.abstractForty patients with endoscopically proved reflux oesophagitis were treated in a randomised study. Treatment was given for six weeks and consisted of either 1 g sucralfate four times a day or 150 mg ranitidine tablet twice daily. Twenty patients received each drug. Clinical evaluation was done weekly and endoscopic evaluation after six weeks. Eight patients on ranitidine and ten patients on sucralfate became asymptomatic at six weeks. Ten patients on ranitidine and twelve patients on sucralfate were endoscopically healed. There was no difference in the effect of ranitidine and sucralfate treatment (p greater than 0.05). Overall tolerance and compliance with the two forms of treatment were good. Though ranitidine has a more convenient dose schedule and is more cost-effective, sucralfate needs further clinical evaluation.en_US
dc.description.affiliationDepartment of Medicine, Government Medical College, Rajendra Hospital, Patiala.en_US
dc.identifier.citationChopra BK, Kazal HL, Mittal PK, Sibia SS. A comparison of the clinical efficacy of ranitidine and sucralfate in reflux oesophagitis. Journal of the Association of Physicians of India. 1992 Mar; 40(3): 162-3en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/94987
dc.language.isoengen_US
dc.source.urihttps://www.japi.orgen_US
dc.subject.meshAdulten_US
dc.subject.meshEsophagitis, Peptic --drug therapyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshRanitidine --therapeutic useen_US
dc.subject.meshSucralfate --therapeutic useen_US
dc.titleA comparison of the clinical efficacy of ranitidine and sucralfate in reflux oesophagitis.en_US
dc.typeClinical Trialen_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
dc.typeRandomized Controlled Trialen_US
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