Ten-year follow-up of corneal cross-linking and refractive surface ablation in patients with asymmetric corneal topography
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Date
2023-09
Journal Title
Journal ISSN
Volume Title
Publisher
All India Ophthalmological Society
Abstract
Purpose: Compare the safety and efficacy of wavefront?guided photorefractive keratotomy (PRK) 6 months after cross?linking (CXL) to wavefront?guided PRK alone for refractive correction in patients with bilateral asymmetric corneal topography. Methods: Prospective randomized clinical trial with 16 patients (32 eyes). CXL with subsequent PRK after 6 months in one eye, and PRK alone was performed in contralateral eyes. The follow?up was 10 years. We analyzed visual outcomes, Scheimpflug topography, and corneal haze evaluation. Results: Eyes in the PRK group showed better results than in the CXL + PRK group. Mean postoperative CDVA was 0.044 logmar (SD, 0.073) in the PRK group and 0.1 logmar (SD, 0.21) in the CXL + PRK group, the mean sphere was + 0.21 (SD, 0.6) D in the PRK group and 0.87 (SD, 2.3) D in the CXL + PRK group, and mean SE was ?0.35 (SD, 0.65) D in the PRK group and 0.62 (SD, 2.32) D in the CXL + PRK group. In one patient, a steepening of 2.5 D and a thinning of 17 ?m occurred in PRK alone group. Two patients in the CXL + PRK group presented corneal haze. The overall complication rate was 18,75% (haze and ectasia). Conclusion: Non?simultaneous CXL and PRK procedures yielded good refractive results, but worse than those obtained with PRK alone. Although one patient in the PRK group developed corneal ectasia, the CXL + PRK group had a higher loss of vision lines, indicating less safety
Description
Keywords
Cornea, corneal stroma, corneal topography, excimer, lasers, photorefractive keratectomy, refractive surgery
Citation
Moscovici Bernardo Kaplan, Rodrigues Pablo Felipe, Dantas Marcos Paulo Suehiro, Okimoto Juliana Taemy, Naves Obidulho Sakassegawa, Taguchi Felipe Marques de Carvalho, Malta Jo鉶 Baptista Nigro Santiago, Campos Mauro. Ten-year follow-up of corneal cross-linking and refractive surface ablation in patients with asymmetric corneal topography. Indian Journal of Ophthalmology. 2023 Sep; 71(9): 3210-3218