Biological behavior and disease pattern of carcinoma gallbladder shown on 64-slice CT scanner: A hospital-based retrospective observational study and our experience.

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dc.contributor.authorDwivedi, A N D
dc.contributor.authorPandey, M
dc.contributor.authorShukla, R C
dc.contributor.authorShukla, V K
dc.contributor.authorGaharwar, S
dc.contributor.authorMaurya, B N
dc.date.accessioned2013-01-22T07:56:04Z
dc.date.available2013-01-22T07:56:04Z
dc.date.issued2012-07
dc.description.abstractPurpose: The aim of this diagnostic observational study was to assess the spread and biological behavior of gallbladder cancer using 64-slice computerized tomography (CT) scanner in this particular geographic belt (eastern Uttar Pradesh, western Bihar, and northern Madhya Pradesh provinces of North India). Indians are ethnically and culturally different from their Western counterparts among whom the incidence of this disease is comparatively low. Subjects and Methods: After systemic examination, all patients (87) were subjected to ultrasonographic examination. All cases were histopathologically proven. Confirmed cases were subjected to volumetric CT examination of abdomen and pelvis, plain, post contrast and delayed phase. Results: Majority of the cases were adenocarcinoma. There was female preponderance with majority belonging to fifth and sixth decades. Commonest presentation was diffuse, irregular, enhancing wall thickening in 49.4%. Majority had invasion of liver parenchyma (74.7%). Cholelithiasis was seen in 48.3% cases. Invasion of biliary radicals was high (13.8-18.4%). Eleven cases had invasion of portal vein and tumor thrombus, with hepatic artery invasion in one case. In two cases, both hepatic artery and portal vein invasion was seen. Portal and peripancreatic nodal metastasis was seen in 58.5%. Distant metastasis was reported. Conclusion: Few studies involving the Indian population have attempted to use multi-row detector CT to define the biological behavior of carcinoma gallbladder. The opinion whether the pathology is operable or non-operable can reasonably be given. This large-scale, single-center study gives insight about the epidemiology and biological behavior of carcinoma gallbladder.en_US
dc.identifier.citationDwivedi A N D, Pandey M, Shukla R C, Shukla V K, Gaharwar S, Maurya B N. Biological behavior and disease pattern of carcinoma gallbladder shown on 64-slice CT scanner: A hospital-based retrospective observational study and our experience. Indian Journal of Cancer. 2012 Jul-Sept; 49(3): 303-308.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/144591
dc.language.isoenen_US
dc.source.urihttps://www.indianjcancer.com/article.asp?issn=0019-509X;year=2012;volume=49;issue=3;spage=303;epage=308;aulast=Dwivedien_US
dc.subjectCarcinoma gall-bladderen_US
dc.subjectmultislice computerised tomographyen_US
dc.subjectbiological behaviouren_US
dc.subject.meshAdult
dc.subject.meshBiological Psychiatry
dc.subject.meshCohort Studies
dc.subject.meshFemale
dc.subject.meshGallbladder Neoplasms --complications
dc.subject.meshGallbladder Neoplasms --diagnosis
dc.subject.meshGallbladder Neoplasms --ultrasonography
dc.subject.meshHumans
dc.subject.meshIndia
dc.subject.meshMale
dc.subject.meshTomography Scanners, X-Ray Computed
dc.titleBiological behavior and disease pattern of carcinoma gallbladder shown on 64-slice CT scanner: A hospital-based retrospective observational study and our experience.en_US
dc.typeArticleen_US
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