Safety and one-year follow-up analysis of percutaneous ASD closure at a tertiary care hospital

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dc.contributor.authorThota, Naga Raghunandanen_US
dc.contributor.authorKosaraju, Kamalakaren_US
dc.contributor.authorRudrapogu, John Satishen_US
dc.contributor.authorNevali, Krishna Prasaden_US
dc.contributor.authorKondaveeti, Thirupathi Raoen_US
dc.date.accessioned2025-08-13T11:15:21Z
dc.date.available2025-08-13T11:15:21Z
dc.date.issued2025-06
dc.description.abstractAim: This study was designed to evaluate the safety and effectiveness of the Cocoon Septal Occluder device (Vascular Innovations Co. Nonthaburi, Thailand) for transcatheter closure of isolated secundum type atrial septal defect (ASD) in Indian patients. Methods: This was a single-center, retrospective, observational study which included patients who underwent transcatheter closure of isolated secundum ASD using the Cocoon Septal Occluder between April 2014 and May 2023. Follow-up assessments up to one-year were conducted through review of hospital medical records, clinic visits, or via telephonic communication with primary care physicians. Results: A total of 400 patients were included in the study, consisting of 28 paediatric (aged ?15 years, 8.14 ± 4.41 years) and 372 adult patients (40.83 ± 13.23 years). The mean defect diameter and device size were 16.75 ± 5.85 mm and 20.43 ± 6.24 mm for paediatric patients, and 21.62 ± 6.87 mm and 24.94 ± 7.28 mm for adult patients, respectively. The device was successfully implanted in all paediatric patients, achieving 100 % closure of the defect with no complications, which persisted through one-year follow-up. In the adult cohort, complete ASD closure was achieved in 99.2 % of patients, with two cases of device embolization and one case of device withdrawal. At one-year follow-up, adult patients experienced 0.3 % late device embolization, 0.8 % pericardial effusion/cardiac tamponade, 0.5 % atrioventricular block, and 0.5 % atrial flutter/fibrillation. No cases of endocarditis, haemolysis, nickel allergy, stroke/transient ischemic attack, or migraine were reported in either paediatric or adult patients. Conclusion: The results demonstrate that Cocoon Septal Occluder is safe and effective in closing isolated secundum ASD during one-year follow-up.en_US
dc.identifier.affiliationsDepartment of Cardiology, NRI Medical College, Chinakakani, Andhra Pradesh, 522503, Indiaen_US
dc.identifier.affiliationsDepartment of Cardiology, NRI Medical College, Chinakakani, Andhra Pradesh, 522503, Indiaen_US
dc.identifier.affiliationsDepartment of Cardiology, NRI Medical College, Chinakakani, Andhra Pradesh, 522503, Indiaen_US
dc.identifier.affiliationsDepartment of Cardiology, NRI Medical College, Chinakakani, Andhra Pradesh, 522503, Indiaen_US
dc.identifier.affiliationsDepartment of Cardiology, NRI Medical College, Chinakakani, Andhra Pradesh, 522503, Indiaen_US
dc.identifier.citationThota Naga Raghunandan, Kosaraju Kamalakar, Rudrapogu John Satish, Nevali Krishna Prasad, Kondaveeti Thirupathi Rao. Safety and one-year follow-up analysis of percutaneous ASD closure at a tertiary care hospital. Indian Heart Journal. 2025 Jun; 77(3): 199-203en_US
dc.identifier.issn0019-4832
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/253340
dc.languageenen_US
dc.publisherElsevieren_US
dc.relation.issuenumber3en_US
dc.relation.volume77en_US
dc.source.urihttps://doi.org/10.1016/j.ihj.2025.03.011en_US
dc.subjectStructural heart defectsen_US
dc.subjectCongenital anomaliesen_US
dc.subjectAtrial septumen_US
dc.subjectTranscatheter closureen_US
dc.titleSafety and one-year follow-up analysis of percutaneous ASD closure at a tertiary care hospitalen_US
dc.typeJournal Articleen_US
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