A Study of Efficacy and Tolerability of Rosehip Extract (Gopo) vs. Ibuprofen (a nsaid) in Treatment of Osteoarthritis in Weight Bearing Joints

Simple item page
dc.contributor.authorLal, Hen_US
dc.contributor.authorSingh, Hen_US
dc.contributor.authorSandhu, KSen_US
dc.contributor.authorSehgal, VKen_US
dc.date.accessioned2019-11-04T04:58:23Z
dc.date.available2019-11-04T04:58:23Z
dc.date.issued2019-07
dc.description.abstractIntroduction: Osteoarthritis is the most common form of arthritis. Osteoarthritis is a joint failure, which occurs due to pathological change in all structure joint. Aim: The aim of the study was to compare the efficacy and tolerability of Rosehip Extract and ibuprofen along with individual effect of both drugs. Materials and Methods: This was an open, randomized, prospective study to compare ROSE HIP Extract and IBUPROFEN for treatment of Osteoarthritis in 100 patients. In this study two comparative groups (50 each) were taken. First group was prescribed 400 mg TDS Ibuprofen and the other group was given Rose hip extract in the form of 275 mg capsule BD. The pain assessment was done through Womac scale and visual analogue scale. The data was collected for efficacy and tolerability for both drugs at 14 days and 3 months. Result: In ibuprofen group, the mean score of pain intensity on womac scale on visit 1 was 39.2 ± 9.58 which was decreased to 11.62 ± 4.97 in the last visit. On VAS scale on visit 1 was 7.26 ± 1.426 and was decreased to 3.36 ± 1.467 at visit 3. In rosehip group. The mean score of pain intensity on WOMAC scale on visit 1 was 38.44 ± 8.45, 30.88 ± 8.068 which was decreased to 26.68 ± 8.474. The mean score of pain intensity at on VAS scale on visit 1 was 7.02 ± 1.06, 5.84 ± 1 and was decreased to 4.6 ± 1.16 at the end of study. Conclusion: Ibuprofen is a better choice than rosehip because it had shown better improvement. Both rosehip and ibuprofen were well tolerated.en_US
dc.identifier.affiliationsJunior Resident, Department of Pharmacology, GMC, Patiala – 147001, Punjab, India; hina.k.lal@gmail.comen_US
dc.identifier.affiliationsEx Professor, Department of Pharmacology, GMC, Patiala – 147001, Punjab, Indiaen_US
dc.identifier.affiliationsAssociate Professor, Department of Orthopaedics, GMC, Patiala – 147001, Punjab, Indiaen_US
dc.identifier.affiliationsProfessor and Head, Department of Pharmacology, GMC, Patiala – 147001, Punjab, India; vijayksehgal@yahoo.comen_US
dc.identifier.citationLal H, Singh H, Sandhu KS, Sehgal VK. A Study of Efficacy and Tolerability of Rosehip Extract (Gopo) vs. Ibuprofen (a nsaid) in Treatment of Osteoarthritis in Weight Bearing Joints. International Journal of Medical and Dental Sciences. 2019 Jul; 8(2): 1754-1758en_US
dc.identifier.issn2454-8952
dc.identifier.issn2320-1118
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/183632
dc.languageenen_US
dc.publisherDr. J.S. Sodhi Memorial Educational Societyen_US
dc.relation.issuenumber2en_US
dc.relation.volume8en_US
dc.source.urihttps://doi.org/10.18311/ijmds/2019/23417en_US
dc.subjectIbuprofenen_US
dc.subjectOsteoarthritisen_US
dc.subjectRose hipen_US
dc.subjectWomac Scaleen_US
dc.subjectGOPOen_US
dc.subjectPharmacologyen_US
dc.titleA Study of Efficacy and Tolerability of Rosehip Extract (Gopo) vs. Ibuprofen (a nsaid) in Treatment of Osteoarthritis in Weight Bearing Jointsen_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
23417-35152-1-PB.pdf
Size:
393.08 KB
Format:
Adobe Portable Document Format
Download
Collections
International Journal of Medical and Dental Sciences