Triangular approach for the diagnosis of monoclonal gammopathy in malignancies.

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dc.contributor.authorKulkarni, Swati Aen_US
dc.contributor.authorShrikhande, Anuradha Ven_US
dc.date.accessioned2009-05-28T07:16:12Z
dc.date.available2009-05-28T07:16:12Z
dc.date.issued2002-06-07en_US
dc.description.abstractMonoclonal Gammopathy (MG) in multiple myeloma (MM) is an established association but its occurrence in nonmyelomatous malignancies and other inflammatory conditions is still a subject of research. We carried out this study to detect monoclonal gammopathy in myelomatous and nonmyelomatous malignancies by adopting the triangular approach of correlating radiologic findings, bone marrow studies and electrophoretic findings. 200 cases of malignancies (25 cases of multiple myeloma and 175 cases of nonmyelomatous malignancies) were studied. Serum and urine electrophoresis was carried out in every case and positive cases were subjected for typing by immunoelectrophoresis (IEP). The incidence of monoclonal gammopathy in nonmyelomatous malignancies was 2.29% (4/175 cases), in epithelial malignancies was 0.8% (1/125 cases) and 6% (3/50 cases) in haematological malignancies. Though the study sample was small, these interesting findings warrant more exhaustive research in this field.en_US
dc.description.affiliationDepartment of Pathology, I.G.M.C., Nagpur, Maharashtra, India.en_US
dc.identifier.citationKulkarni SA, Shrikhande AV. Triangular approach for the diagnosis of monoclonal gammopathy in malignancies. Indian Journal of Cancer. 2002 Jun; 39(2): 45-54en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/51115
dc.language.isoengen_US
dc.source.urihttps://www.indianjcancer.comen_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshCross-Sectional Studiesen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshIncidenceen_US
dc.subject.meshIndia --epidemiologyen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshMultiple Myeloma --complicationsen_US
dc.subject.meshNeoplasms --complicationsen_US
dc.subject.meshParaproteinemias --diagnosisen_US
dc.titleTriangular approach for the diagnosis of monoclonal gammopathy in malignancies.en_US
dc.typeJournal Articleen_US
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