Evaluation of cognitive brain functions in caffeine users: a P3 evoked potential study.

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dc.contributor.authorDixit, Abhinaven_US
dc.contributor.authorVaney, Neelamen_US
dc.contributor.authorTandon, O Pen_US
dc.date.accessioned2006-04-21en_US
dc.date.accessioned2009-06-01T08:10:23Z
dc.date.available2006-04-21en_US
dc.date.available2009-06-01T08:10:23Z
dc.date.issued2006-04-21en_US
dc.description.abstractCaffeine is one of the most widely consumed stimulant drugs of the modern world. It brings about a feeling of well-being, relaxation, increased alertness and concentration. Its effects have been studied on brain function and behavior using mood questionnaires, reaction time tests, memory tests, EEG and of late Event Related Potentials (ERPs). This study evaluates the response of caffeine on ERPs and Reaction Time (RT) using auditory "oddball" paradigm. Forty undergraduate medical students volunteered for the study and their ERPs and RT were recorded before and after 40 minutes of ingestion of caffeine. There was a non-significant decrease in latency of N1, P2, N2 and P3 and a significant decrease in Reaction Time after caffeine consumption. The amplitude of P3 showed a significant increase after intake of caffeine. The results of this study indicate that caffeine leads to facilitation of information processing and motor output response of the brain.en_US
dc.description.affiliationDepartment of Physiology, University College of Medical Sciences and G.T.B. Hospital, Dilshad Garden, Delhi 110 095. abhinavdr@yahoo.comen_US
dc.identifier.citationDixit A, Vaney N, Tandon OP. Evaluation of cognitive brain functions in caffeine users: a P3 evoked potential study. Indian Journal of Physiology and Pharmacology. 2006 Apr-Jun; 50(2): 175-80en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/108712
dc.language.isoengen_US
dc.source.urihttps://www.ijpp.comen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshBrain --drug effectsen_US
dc.subject.meshCaffeine --pharmacologyen_US
dc.subject.meshCognition --drug effectsen_US
dc.subject.meshEvoked Potentials --drug effectsen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshReaction Time --drug effectsen_US
dc.subject.meshReceptors, Dopamine --drug effectsen_US
dc.subject.meshReceptors, Purinergic P1 --drug effectsen_US
dc.titleEvaluation of cognitive brain functions in caffeine users: a P3 evoked potential study.en_US
dc.typeJournal Articleen_US
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