Ethnobotany & ethnopharmacology of Tabernaemontana divaricata.

dc.contributor.authorPratchayasakul, Wasanaen_US
dc.contributor.authorPongchaidecha, Anchaleeen_US
dc.contributor.authorChattipakorn, Niponen_US
dc.contributor.authorChattipakorn, Siripornen_US
dc.date.accessioned2008-04-26en_US
dc.date.accessioned2009-05-27T07:07:07Z
dc.date.available2008-04-26en_US
dc.date.available2009-05-27T07:07:07Z
dc.date.issued2008-04-26en_US
dc.description119 references.en_US
dc.description.abstractTabernaemontana divaricata a common garden plant in tropical countries has been used as a traditional medicine. However, no recent review articles of T. divaricata, particularly discussing its pharmacological properties, are available. This review presents the ethnobotany and ethnopharmacology of T. divaricata as well as its potential therapeutic benefits especially of the alkaloidal and non-alkaloidal constituents. Included, are the characteristics of 66 alkaloids isolated and identified from T. divaricata. Non-alkaloids including the enzymes, pyrolytic oil, hydrocarbons, terpenoid and phenolic acids are also documented. Chemotaxonomic aspects of each alkaloid as well as information regarding the pharmacology of crude extracts and individual alkaloids from T. divaricata have been assembled and appraised. The beneficial properties of T. divaricata are antioxidant, anti-infection, anti-tumour action, analgesia and the enhancement of cholinergic activity in both peripheral and central nervous systems. The augmentation of cholinergic function may be of therapeutic benefit for many neurodegenerative diseases, particularly myasthenia gravis and Alzheimer's disease.en_US
dc.description.affiliationCardiac Electrophysiology Research & Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.en_US
dc.identifier.citationPratchayasakul W, Pongchaidecha A, Chattipakorn N, Chattipakorn S. Ethnobotany & ethnopharmacology of Tabernaemontana divaricata. Indian Journal of Medical Research. 2008 Apr; 127(4): 317-35en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/19375
dc.language.isoengen_US
dc.source.urihttps://icmr.nic.in/ijmr/ijmr.htmen_US
dc.subject.meshEthnobotanyen_US
dc.subject.meshEthnopharmacologyen_US
dc.subject.meshHumansen_US
dc.subject.meshPhytotherapyen_US
dc.subject.meshPlant Extracts --chemistryen_US
dc.subject.meshTabernaemontana --chemistryen_US
dc.titleEthnobotany & ethnopharmacology of Tabernaemontana divaricata.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
dc.typeReviewen_US
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