Battle on two fronts: Fournier’s gangrene as a devastating complication of targeted radiotherapy for advanced adenocarcinoma rectum
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Date
2025-06
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Mansa STM Publishers
Abstract
Fournier’s gangrene (FG), as a complication of rectal carcinoma, is exceptionally rare and life-threatening. This case reports an unusual presentation of radiotherapy-induced FG in a 75-year-old male patient with advanced rectal adenocarcinoma. Multiple surgical debridements provided temporary stabilization, supported by targeted antibiotics and airway management. However, progressive polymicrobial sepsis necessitated a multidisciplinary approach, which was unsuccessful due to underlying poor prognostic factors. This case underscores the need for standardized clinical guidelines and management protocols to improve patient outcomes and reduce mortality in similar cases.
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Keywords
Adenocarcinoma rectum, Adverse effects of radiotherapy, Fournier’s gangrene, Necrotizing fasciitis, Pelvic radiotherapy, Radiotherapy complications
Citation
Athiyaman A, Kumar SS, Victor VP. . Battle on two fronts: Fournier’s gangrene as a devastating complication of targeted radiotherapy for advanced adenocarcinoma rectum . Indian Journal of Case Reports. 2025 Jun; 11(6): 277-279